1. Gene
  2. Cyp2a2 - cytochrome P450, family 2, subfamily a, polypeptide 2 Gene

Cyp2a2 - cytochrome P450, family 2, subfamily a, polypeptide 2 Gene

Rattus norvegicus

Also known as CYP2A21; RATCYP2A21

Gene ID: 24895 | Gene type: protein coding

About Cyp2a2

Summary

Enables steroid hydroxylase activity. Predicted to be involved in coumarin metabolic process; epoxygenase P450 pathway; and xenobiotic metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in nicotine dependence and warfarin resistance. Orthologous to human CYP2A13 (Cytochrome P450 family 2 subfamily A member 13); CYP2A6 (Cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (Cytochrome P450 family 2 subfamily A member 7). [provided by Alliance of Genome Resources, Apr 2022]

Cyp2a2 Products(2)

mRNA Protein Name
NM_012693.1 NP_036825.1 cytochrome P450 2A2
NM_012693.1 NP_036825.1 cytochrome P450 2A2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables steroid hydroxylase activity IDA
IDA: Inferred from direct assay
3192524 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome P450 2A2

CYPIIA2

Cytochrome P450 IIA2

P450-UT-4

cytochrome P450, subfamily 2A, polypeptide 1

cytochrome P450, subfamily 2A, polypeptide 2

cytochrome P450-UT-4

hepatic steroid hydroxylase IIA2 (CYP2A2)

testosterone 15-alpha-hydroxylase