2-Naphthol-d7
Based on 1 Customer Validation
2-Naphthol-d7 is the deuterium labeled 2-Naphthol. 2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2).
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- Pureza : 95.00%
- No. CAS: 78832-54-9
- Fòrmula: C10HD7O
- Peso molecular:151.22
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
Descripciòn
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Aplicación
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 78832-54-9
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Unlabeled CAS 135-19-3
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Appearance Solid
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Peso molecular 151.22
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Fòrmula C10HD7O
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Color White to off-white
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SMILES
OC1=C([2H])C2=C(C([2H])=C([2H])C([2H])=C2[2H])C([2H])=C1[2H]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (698 KB)
- English - EN (698 KB)
- Français - FR (698 KB)
- Deutsch - DE (698 KB)
- Norwegian - NO (698 KB)
- Español - ES (698 KB)
- Swedish - SV (698 KB)
- Italian - IT (698 KB)
- Korean - KR (698 KB)
- Portuguese - PT (698 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Kapuci M, et al. Determination of cytotoxic and genotoxic effects of naphthalene, 1-naphthol and 2-naphthol on human lymphocyte culture. Toxicol Ind Health. 2014 Feb;30(1):82-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2-Naphthol-d7 Related Classifications
HY-Y0110S1 Related Classifications
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