2. Gene
  3. Mr1 - major histocompatibility complex, class I-related Gene

Mr1 - major histocompatibility complex, class I-related Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hlals

Gene ID: 25119 | Gene type: protein coding

About Mr1

Summary

Predicted to enable T cell receptor binding activity and beta-2-microglobulin binding activity. Predicted to be involved in several processes, including T cell differentiation in thymus; defense response to Gram-positive bacterium; and positive regulation of T cell mediated cytotoxicity directed against tumor cell target. Predicted to act upstream of or within defense response to Gram-negative bacterium. Predicted to be located in endoplasmic reticulum membrane; endosome membrane; and plasma membrane. Predicted to be part of MHC class I protein complex. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human MR1 (major histocompatibility complex, class I-related). [provided by Alliance of Genome Resources, Apr 2022]

Mr1 Products(1)

mRNA Protein Name
NM_001100635.1 NP_001094105.1 major histocompatibility complex class I-related gene protein precursor
Protein Preferred Names Protein Names

major histocompatibility complex class I-related gene protein

MHC class I-like sequence

MHC class I-related gene protein

histocompatibility-2 complex class 1-like sequence

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-157282 Photolumazine I / Phase 4
Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-124004 Acetyl-6-formylpterin 95.0% Unkown
HY-126855 Cholic acid 7-sulfate 99.92% Unkown
HY-32955 2-Chloropyridine-5-boronic acid 99.96% Unkown
HY-W168754 DB28 Inhibitor 99.92% Unkown
HY-157281 Photolumazine III 99.96% Unkown
HY-157194 RL-6-Me-7-OH 96.56% Unkown
HY-182894 MR1-114 Inhibitor / Unkown
HY-P11249 Mr1.1[S4Dap, C16Pen] Inhibitor / Unkown
HY-RS08637 MR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10777 PNKD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-126855S Cholic acid 7-sulfate-d4 / Unkown
HY-163122 5-Formylsalicylic acid 99.54% Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990134 Anti-Mouse CD40L/CD154 Antibody (MR-1) Inhibitor 99.62% Unkown
HY-P990269 Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) Inhibitor 95.00% Unkown
HY-P990270 Anti-Mouse CD40L/CD154 (D265A) Antibody (MR-1) / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mr1 NCBI NCBI:3140
Macaca fascicularis Mr1 NCBI
Mus musculus Mr1 NCBI NCBI:15064