NTRK1 - neurotrophic receptor tyrosine kinase 1 Gene

Bos taurus

Also known as TRKA

Gene ID: 353111 | Gene type: protein coding

About NTRK1

Primary_assembly 3: 13,971,853-13,989,966 reverse strand.ARS-UCD1.2:CM008170.2

This gene has 3 transcripts (splice variants), 200 orthologues and 56 paralogues.

mRNA	Protein	Name
XM_024989929.1	XP_024845697.1	high affinity nerve growth factor receptor isoform X2
XM_002685966.6	XP_002686012.2	high affinity nerve growth factor receptor isoform X1
XM_024989930.1	XP_024845698.1	high affinity nerve growth factor receptor isoform X3

LRR_1

LRR_8

LRR_1

TPKR_C2

Ig_TrkABC_d4

IgI_TrKABC_d5

PTKc_TrkA

Protein Preferred Names

Protein Names

high affinity nerve growth factor receptor

neurotrophic tyrosine kinase, receptor, type 1

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-131003A	Taletrectinib free base	Inhibitor	/	Phase 3
HY-131003	Taletrectinib	Inhibitor	99.63%	Phase 2

Pre-clinical Phase

Bioactive Molecules (13)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-101977A	(R,S)-Selitrectinib	Inhibitor	/	Unkown
HY-144451	TRK-IN-12	Inhibitor	/	Unkown
HY-156086	TRK-IN-24	Inhibitor	/	Unkown
HY-180172	TRK-IN-33		/	Unkown
HY-181052	PROTAC NTRK1 degrader-1	Degrader	/	Unkown
HY-185545	NTRK1-ligand-1	Ligand	/	Unkown
HY-E70869	TRKA(NTRK1) Recombinant Human Active Protein Kinase		/	Unkown
HY-RS09628	NTRK1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS09629	Ntrk1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS09630	Ntrk1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-185546	CRBN ligand-900 Gly		/	Unkown
HY-D3447	LPd peroxida probe-2		/	Unkown
HY-W1115186	CRBN ligand-900		/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990589	GBR-900		/	Unkown

Species	Symbol	Source	ID
Homo sapiens	NTRK1	NCBI	NCBI:4914
Canis familiaris	NTRK1	NCBI	NCBI:490404
Mus musculus	NTRK1	NCBI	NCBI:18211
Leporidae	NTRK1	NCBI
Rattus norvegicus	NTRK1	NCBI	NCBI:59109

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