CRBN ligand-900 Gly
CRBN ligand-900 Gly is a synthesized E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugate) that incorporates a CRBN ligand and a linker. CRBN ligand-900 Gly can be connected to the target protein ligand to form a PROTAC NTRK1 degrader-1 (HY-181052).
For research use only. We do not sell to patients.
- CAS No.: 2922276-95-5
- Formula: C17H23N5O3
- Molecular Weight:345.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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Cereblon |
A PROTAC consists of two distinct ligands linked by a linker: one is a ligand for an E3 ubiquitin ligase, and the other is a ligand for a target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2922276-95-5
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Molecular Weight 345.40
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Formula C17H23N5O3
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SMILES
NCC(N1CCN(C2=CC=C(NC3CCC(NC3=O)=O)C=C2)CC1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CRBN ligand-900 Gly Related Classifications
HY-185546 Related Classifications
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