CRBN ligand-900
CRBN ligand-900 is an E3 ligase ligand that can be used in the recruitment of CRBN protein. CRBN ligand-900 can be connected to the NTRK1 ligand (HY-185545) by a linker to synthesis of PROTAC NTRK1 degrader-1 (HY-181052).
For research use only. We do not sell to patients.
- CAS No.: 2259851-44-8
- Formula: C15H20N4O2
- Molecular Weight:288.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cereblon |
A PROTAC comprises two distinct ligands linked by a linker: one is a ligand for an E3 ubiquitin ligase, and the other is a ligand for a target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2259851-44-8
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Molecular Weight 288.34
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Formula C15H20N4O2
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SMILES
O=C(C(NC1=CC=C(N2CCNCC2)C=C1)CC3)NC3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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