2259851-44-8
2259851-44-8
Chemical Structure
CRBN ligand-900
- CAS No.: 2259851-44-8
- Formula:C15H20N4O2
- Molecular Weight:288.34
InChIKey: CHXUEVQRXAXREA-UHFFFAOYSA-N
SMILES: O=C(C(NC1=CC=C(N2CCNCC2)C=C1)CC3)NC3=O
Biological Activity: CRBN ligand-900 is an E3 ligase ligand that can be used in the recruitment of CRBN protein. CRBN ligand-900 can be connected to the NTRK1 ligand (HY-185545) by a linker to synthesis of PROTAC NTRK1 degrader-1 (HY-181052)[1].
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CRBN ligand-900 | CRBN ligand-900 is an E3 ligase ligand that can be used in the recruitment of CRBN protein. CRBN ligand-900 can be connected to the NTRK1 ligand (HY-185545) by a linker to synthesis of PROTAC NTRK1 degrader-1 (HY-181052). | |||||||||||||||||||||
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References
Keywords
