ZNF593 - zinc finger protein 593 Gene

Also Known as ZT86

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51042

Summary

Enables preribosome binding activity and zinc ion binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in colon (RPKM 5.2), kidney (RPKM 4.4) and 25 other tissues.

ZNF593 Products (1)

mRNA Protein Name
NM_015871.5 NP_056955.2 zinc finger protein 593

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables preribosome binding IDA
IDA: Inferred from direct assay
32669547 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables zinc ion binding IMP
IMP: Inferred from mutant phenotype
18287285 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding IGI
IGI: Inferred from genetic interaction
9115366 GOA
involved in positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
9115366 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF593 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF593 O00488 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra
ZNF593 O00488 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
Intra
ZNF593 O00488 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra
ZNF593 O00488 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
ZNF593 O00488 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
ZNF593 O00488 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16147 ZNF503 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16155 ZNF592 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16156 ZNF595 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16157 ZNF598 Human Pre-designed siRNA Set A Pre-designed Set / Unkown