173026-17-0
173026-17-0
Chemical Structure
ALT-2074
Synonym(s): BXT-51072
- CAS No.: 173026-17-0
- Formula:C10H13NSe
- Molecular Weight:226.18
InChIKey: FXRYWOJYVGJZLE-UHFFFAOYSA-N
SMILES: CC1(C)CN[Se]C2=C1C=CC=C2
Biological Activity: ALT-2074 (BXT-51071) is an orally active catalytic analogue of glutathione peroxidase. ALT-2074 is an inhibitor of human CYP3A, with its IC50 value ranging from 2.0 to 2.6 μM. ALT-2074 shows only a weak inhibitory effect on CYP3A in vivo, suggesting that it may not significantly affect the metabolism of CYP3A substrate drugs. ALT-2074 can be used to study inflammatory diseases characterized by reactive oxygen species, such as acute coronary syndrome[1].
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ALT-2074 | ALT-2074 (BXT-51071) is an orally active catalytic analogue of glutathione peroxidase. ALT-2074 is an inhibitor of human CYP3A, with its IC50 value ranging from 2.0 to 2.6 μM. ALT-2074 shows only a weak inhibitory effect on CYP3A in vivo, suggesting that it may not significantly affect the metabolism of CYP3A substrate drugs. ALT-2074 can be used to study inflammatory diseases characterized by reactive oxygen species, such as acute coronary syndrome. | |||||||||||||||||||||
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