RPS27L - ribosomal protein S27 like Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51065

Summary

This gene encodes a protein sharing 96% amino acid similarity with ribosomal protein S27, which suggests the encoded protein may be a component of the 40S ribosomal subunit. [provided by RefSeq, Jul 2008]
Ubiquitous expression in colon (RPKM 73.0), kidney (RPKM 50.8) and 25 other tissues.

RPS27L Products (1)

mRNA Protein Name
NM_015920.4 NP_057004.1 ribosomal protein eS27-like

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cysteine-type endopeptidase activator activity involved in apoptotic process IDA
IDA: Inferred from direct assay
17057733 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
21170087 GOA
enables translation activator activity IDA
IDA: Inferred from direct assay
18056458 GOA
Biological Process GO Annotation Evidence References Source
involved in DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IDA
IDA: Inferred from direct assay
18056458 GOA
involved in activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
IDA: Inferred from direct assay
17057733 GOA
involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IDA
IDA: Inferred from direct assay
17057733 GOA
involved in mitotic G1 DNA damage checkpoint signaling IMP
IMP: Inferred from mutant phenotype
18056458 GOA
involved in positive regulation of translation IDA
IDA: Inferred from direct assay
18056458 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
18056458 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RPS27L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RPS27L Q71UM5 MDM2 Homo sapiens Q00987
Pull Down
21170087
Intra
RPS27L Q71UM5 MDM2 Homo sapiens Q00987
Confocal
21170087
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS20593 Rps27a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12238 RPS27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12239 RPS27A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27101 Rps27a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown