1374107-46-6

THK-5105 Chemical Structure
1374107-46-6

Chemical Structure

THK-5105

  • CAS No.: 1374107-46-6
  • Formula:C20H21FN2O2
  • Molecular Weight:340.39

IUPAC Name: 1-((2-(4-(dimethylamino)phenyl)quinolin-6-yl)oxy)-3-fluoropropan-2-ol

InChIKey: YECXMTCPEPHEAA-UHFFFAOYSA-N

SMILES: OC(CF)COC1=CC=C2N=C(C3=CC=C(N(C)C)C=C3)C=CC2=C1

Biological Activity: THK-5105, an arylquinoline derivative, displays high binding affinity to tau fibrils. THK-5105 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD)  brain homogenates. 18F-THK-5105 has the potential to act as a tau imaging PET probe[1].

Cat. No. Product Name Purity Description Pricing
HY-101181
THK-5105 98.67% THK-5105, an arylquinoline derivative, displays high binding affinity to tau fibrils. THK-5105 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD)  brain homogenates. 18F-THK-5105 has the potential to act as a tau imaging PET probe.
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