TBL1Y Antibody (YA5165)
(Synonyms: TBL1Y; TBL1; F-box-like/WD repeat-containing protein TBL1Y; Transducin beta-like protein 1Y; Transducin-beta-like protein 1; Y-linked)
Based on 1 Customer Validation
TBL1Y Antibody (YA5165) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TBL1Y.
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Host:
Mouse
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Application:
WB
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Reactivity :
Human, Mouse, Rat, Dog, Pig
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Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:1000-1:2000 |
Product Details
TBL1Y Antibody (YA5165) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TBL1Y.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat, Dog, Pig
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Calculated Molecular Weight Predicted band size: 57 kDa;
Purified recombinant human TBL1Y protein fragments expressed in E.coli.
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TBL1Y is a F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange
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Subcellular Localization
Nucleus
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Expression
Tissue_specificity:Fetal brain and prostate. Expressed in the cochlear spiral ganglion neurons, and in outer and inner hair cells (PubMed:30341416) -
Subunit
Probable component of the N-Cor repressor complex and some E3 ubiquitin ligase complex. Interacts with NCOR2 (PubMed:30341416)
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SwissProt ID
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Synonyms
TBL1Y; TBL1; F-box-like/WD repeat-containing protein TBL1Y; Transducin beta-like protein 1Y; Transducin-beta-like protein 1; Y-linked
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