ADAM17 - ADAM metallopeptidase domain 17 Gene

Species: Bos taurus

Gene Type: protein coding
Gene ID: 517541

About ADAM17

Primary_assembly 11: 87,917,749-87,960,440 forward strand.ARS-UCD1.2:CM008178.2

This gene has 1 transcript (splice variant), 282 orthologues and 36 paralogues.

ADAM17 Products (2)

mRNA Protein Name
XM_010810303.3 XP_010808605.1 disintegrin and metalloproteinase domain-containing protein 17 isoform X2
XM_002691486.6 XP_002691532.1 disintegrin and metalloproteinase domain-containing protein 17 isoform X1

ADAM17 Protein Structure

Pep_M12B_propep

Pep_M12B_propep: cl03265 (47 - 164)

ZnMc_TACE_like

ZnMc_TACE_like: cd04270 (220 - 474)

DISIN

DISIN: smart00050 (481 - 557)

ADAM17_MPD

ADAM17_MPD: pfam16698 (578 - 639)

  • 0
  • 200
  • 400
  • 600
  • 825 a.a.
Protein Preferred Names Protein Names

disintegrin and metalloproteinase domain-containing protein 17

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-10293 Aderbasib Inhibitor 99.44% Phase 2

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-115670 GW280264X Inhibitor 99.30% Unkown
HY-16657 TAPI-1 Inhibitor 99.36% Unkown
HY-110397 KP-457 Inhibitor 99.18% Unkown
HY-120852 JG26 Inhibitor 98.14% Unkown
HY-P3722A Mca-PLAQAV-Dpa-RSSSR-NH2 TFA 99.54% Unkown
HY-P3722 Mca-PLAQAV-Dpa-RSSSR-NH2 Substrate 99.33% Unkown
HY-175876 ADAM17-IN-1 Inhibitor / Unkown
Bioactive MoleculesInhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992406 MEDI-3622 Inhibitor / Unkown
HY-P992341 D8P1C1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ADAM17 NCBI NCBI:6868
Mus musculus ADAM17 NCBI NCBI:11491
Rattus norvegicus ADAM17 NCBI NCBI:57027