SEPTIN11 - septin 11 Gene

Also Known as SEPT11; Septin-11

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55752

Summary

SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).[supplied by OMIM, Jul 2009]
Ubiquitous expression in placenta (RPKM 24.6), fat (RPKM 23.3) and 25 other tissues.

SEPTIN11 Products (2)

mRNA Protein Name
NM_001306147.2 NP_001293076.1 septin-11 isoform 1
NM_018243.4 NP_060713.1 septin-11 isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15485874 GOA
Cellular Component GO Annotation Evidence References Source
part of septin complex IDA
IDA: Inferred from direct assay
15485874 GOA
located in stress fiber IDA
IDA: Inferred from direct assay
15485874 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SEPTIN11 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SEPTIN11 Q9NVA2 SEPTIN7 Homo sapiens Q16181
Anti Tag CoIP
33961781
Intra
SEPTIN11 Q9NVA2 SEPTIN7 Homo sapiens Q16181
Anti Tag CoIP
35271311
Intra
SEPTIN11 Q9NVA2 SEPTIN5 Homo sapiens Q99719
Y2H
16767699
Intra
SEPTIN11 Q9NVA2 SEPTIN5 Homo sapiens Q99719
FRET
16767699
Intra
SEPTIN11 Q9NVA2 SEPTIN5 Homo sapiens Q99719
Y2H Array
32296183
Intra
SEPTIN11 Q9NVA2 SEPTIN5 Homo sapiens Q99719
Anti Tag CoIP
33961781
Intra
SEPTIN11 Q9NVA2 SEPTIN5 Homo sapiens Q99719
Y2H Prey Pooling
32296183
Intra
SEPTIN11 Q9NVA2 SEPTIN5 Homo sapiens Q99719
Anti Tag CoIP
35271311
Intra
SEPTIN11 Q9NVA2 SEPTIN1 Homo sapiens Q8WYJ6
Y2H Prey Pooling
32296183
Intra
SEPTIN11 Q9NVA2 SEPTIN1 Homo sapiens Q8WYJ6
Y2H Array
32296183
Intra
SEPTIN11 Q9NVA2 SEPTIN9 Homo sapiens Q9UHD8
Anti Tag CoIP
35271311
Intra
SEPTIN11 Q9NVA2 SEPTIN9 Homo sapiens Q9UHD8
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12681 SEPTIN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown