1285910-03-3
1285910-03-3
Chemical Structure
Nisoldipine-d6
Synonym(s): BAY-k 5552-d6
- CAS No.: 1285910-03-3
- Formula:C20H18D6N2O6
- Molecular Weight:394.45
IUPAC Name: 3-methyl 5-(2-(methyl-d3)propyl-3,3,3-d3) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey: VKQFCGNPDRICFG-WFGJKAKNSA-N
SMILES: O=C(C(C(C(C=CC=C1)=C1[N](=O)=O)C(C(OC)=O)=C2C)=C(N2)C)OCC(C([2H])([2H])[2H])C([2H])([2H])[2H]
Biological Activity: Nisoldipine-d6 is the deuterium labeled Nisoldipine. Nisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with an IC50 of 10 nM.
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Nisoldipine-d6 | Nisoldipine-d6 is the deuterium labeled Nisoldipine. Nisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with an IC50 of 10 nM. | |||||||||||||||||||||
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Nisoldipine (Standard) | 99.55% | Nisoldipine (Standard) is the analytical standard of Nisoldipine. This product is intended for research and analytical applications. Nisoldipine (BAY-k 5552; Sular) is a highly efficient and specific L-type Cav1.2 channel blocker with an IC50 of 10 nM. | ||||||||||||||||||||
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Nisoldipine-d4 | Nisoldipine-d4 (BAY-k 5552-d4) is the deuterium labeled Nisoldipine. Nisoldipine(BAY-k 5552) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. | |||||||||||||||||||||
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Nisoldipine-d7 | Nisoldipine-d7 (BAY-k 5552-d7) is the deuterium labeled Nisoldipine. Nisoldipine(BAY-k 5552) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. | |||||||||||||||||||||
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Nisoldipine-d3 | Nisoldipine-d3 is deuterated labeled Nisoldipine (HY-17402). Nisoldipine (BAY-k 5552; Sular) is a highly efficient and specific L-type Cav1.2 channel blocker with an IC50 of 10 nM. | |||||||||||||||||||||
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Nisoldipine | 99.56% | Nisoldipine (BAY-k 5552; Sular) is an orally active and blood-brain barrier-penetrating dihydropyridine calcium antagonist, with greater vascular selectivity than other calcium channel antagonists. Nisoldipine inhibits calcium influx and blocks voltage-gated calcium channels. Nisoldipine dilates coronary and systemic arteries. Nisoldipine has antihypertensive and anti-anginal activity. Nisoldipine also displays neuroprotective and antiviral activity. | ||||||||||||||||||||
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