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RPS11 - ribosomal protein S11 Gene

Also Known as S11

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 6205

About RPS11

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:49,496,434-49,499,708 (from NCBI)

This gene has 9 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in ovary (RPKM 1700.9), bone marrow (RPKM 1027.8) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]

RPS11 Products (1)

mRNA	Protein	Name
NM_001015.5	NP_001006.1	40S ribosomal protein S11

RPS11 Protein Structure

Ribosomal_S17

0
100
158 a.a.

Protein Preferred Names	Protein Names
40S ribosomal protein S11	small ribosomal subunit protein uS17

RPS11 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	RPS11	P62280	RPS8	Homo sapiens	P62241	Crosslink	30021884
Intra	RPS11	P62280	RPS8	Homo sapiens	P62241	Anti Tag CoIP	35271311
Intra	RPS11	P62280	MAP3K14	Homo sapiens	Q99558	TAP	14743216
Intra	RPS11	P62280	LRRK2	Homo sapiens	Q5S007	Protein Kinase Assay	24725412

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Cyclosporiasis	Cyclosporosis Cyclospora Infection
Diamond-Blackfan Anemia	Congenital Pure Red Cell Aplasia Aase Syndrome Erythrogenesis Imperfecta Anemia, Diamond-Blackfan Congenital Hypoplastic Anemia Aase-Smith Ii Syndrome Bds Blackfan-Diamond Anemia Congenital Prca Congenital Hypoplastic Anemia, Blackfan-Diamond Type Dba Blackfan - Diamond Syndrome Chronic Constitutional Pure Red Cell Anaemia Anemia Diamond Blackfan Type Anemia Congenital Erythroid Hypoplastic Aregenerative Anemia Chronic Congenital Blackfan Diamond Syndrome Red Cell Aplasia, Pure Hereditary Aase-Smith Syndrome Ii Bda Blackfan Diamond Anemia Blackfan-Diamond Disease Blackfan-Diamond Syndrome Chronic Congenital Agenerative Anemia Congenital Erythroid Hypoplastic Anemia Congenital Hypoplastic Anemia Of Blackfan And Diamond Congenital Pure Red Cell Anemia Hypoplastic Congenital Anemia Inherited Erythroblastopenia Pure Hereditary Red Cell Aplasia Anemia, Hypoplastic, Congenital Anemia Hypoplastic Congenital Fanconi Anemia Constitutional Aplastic Anemia Diamond-Blackfan Anemia 1 Aase Smith Syndrome 2 Congenital Red Cell Aplasia Red Cell Aplasia Of Infants Pure Red Cell Aplasia Of Infants Congenital Red Cell Aplastic Anaemia Congenital Pure Red Cell Anaemia Congenital Erythroid Hypoplasia Pearson Marrow-Pancreas Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12221	RPS11 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	RPS11	RGD	RGD:621026
Canis familiaris	RPS11	VGNC	VGNC:53968
Bos taurus	RPS11	VGNC	VGNC:53041
Felis catus	RPS11	VGNC	VGNC:103062
Mus musculus	RPS11	MGD	MGI:1351329
Others	RPS11	NCBI