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79074

" within the MedChemExpress (MCE) catalog. Here are the results you might be looking for.

By Targets:	Amyloid-β (1) Antibiotic (1) Apoptosis (1) DNA/RNA Synthesis (1) HBV (1) MicroRNA (12) Mitophagy (1) PINK1/Parkin (1) Raf (1) Reference Standards (1) Thymidylate Synthase (1)
By Research Areas:	Cancer (14) Infection (2) Inflammation/Immunology (2) Neurological Disease (1)
Oligonucleotides:	miRNA mimics (3) miRNA antagomirs (3) miRNA agomirs (3) MicroRNAs (12) miRNA inhibitors (3)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-18997

PLX7904 3 Publications Verification PB04	Raf	Cancer
PLX7904 is a potent and selective BRAF inhibitor, with IC₅₀ of appr 5 nM against BRAF ^V600E in mutant RAS expressing cells.

HY-174806

Y040-7904 7-(β-D-Galactopyranosyloxy)-4-phenylchromen-2-one	Mitophagy PINK1/Parkin Amyloid-β	Neurological Disease
Y040-7904 is a mitophagy activator. Y040-7904 enhances mitophagy by promoting mitochondria transport to autophagosomes and the fusion of autophagosomes with autolysosomes. Y040-7904 induces mitophagy through the SIRT1/FoxO3 pathway. Y040-7904 upregulates the levels of Parkin, PINK1, and LC3II/I. Y040-7904 reduces amyloid-β (Aβ) accumulation in both in vitro and in vivo models of Alzheimer’s disease.

HY-145579

Linvencorvir RG7907; RO7049389	HBV Apoptosis	Infection Inflammation/Immunology
Linvencorvir (RG7907) is an orally active Hepatitis B virus core protein allosteric modulator. Linvencorvir induces Apoptosis. Linvencorvir has antiviral activity against HBV .

HY-10823

*OSI-7904L* GW1843; 1843U89; OSI-7904	Thymidylate Synthase DNA/RNA Synthesis	Cancer
OSI-7904L (GW1843; 1843U89; OSI-7904) is a thymidylate synthase (TS) inhibitor with a K_i of 90 pM. OSI-7904L blocks de novo synthesis of thymidine nucleotides, DNA synthesis and induces cell death. OSI-7904L inhibits the growth of human cells, induces tumor regression, and achieves durable antitumor effects in mouse xenograft models. OSI-7904L can be used in research related to colon adenocarcinoma .

HY-R02438

*hsa-miR-7974* mimic**	MicroRNA	Cancer
hsa-miR-7974 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-7974 mimic hsa-miR-7974 mimic

HY-RI02438

*hsa-miR-7974* inhibitor**	MicroRNA	Cancer
hsa-miR-7974 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-7974 inhibitor hsa-miR-7974 inhibitor

HY-R03893

*mmu-miR-7074-3p mimic*	MicroRNA	Cancer
mmu-miR-7074-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-7074-3p mimic mmu-miR-7074-3p mimic

HY-145579R

Linvencorvir (Standard) RG7907 (Standard); RO7049389 (Standard)	Antibiotic Reference Standards	Infection Inflammation/Immunology
Bendiocarb (Standard) is the analytical standard of Bendiocarb. This product is intended for research and analytical applications. Linvencorvir (RG7907) is an orally active Hepatitis B virus core protein allosteric modulator. Linvencorvir induces Apoptosis. Linvencorvir has antiviral activity against HBV .

HY-R02438A

*hsa-miR-7974* agomir**	MicroRNA	Cancer
hsa-miR-7974 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-7974 agomir hsa-miR-7974 agomir

HY-RI02438A

*hsa-miR-7974* antagomir**	MicroRNA	Cancer
hsa-miR-7974 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-7974 antagomir hsa-miR-7974 antagomir

HY-RI03894

*mmu-miR-7074-5p inhibitor*	MicroRNA	Cancer
mmu-miR-7074-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-7074-5p inhibitor mmu-miR-7074-5p inhibitor

HY-R03894A

*mmu-miR-7074-5p agomir*	MicroRNA	Cancer
mmu-miR-7074-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7074-5p agomir mmu-miR-7074-5p agomir

HY-R03894

*mmu-miR-7074-5p mimic*	MicroRNA	Cancer
mmu-miR-7074-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-7074-5p mimic mmu-miR-7074-5p mimic

HY-R03893A

*mmu-miR-7074-3p agomir*	MicroRNA	Cancer
mmu-miR-7074-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7074-3p agomir mmu-miR-7074-3p agomir

HY-RI03894A

*mmu-miR-7074-5p antagomir*	MicroRNA	Cancer
mmu-miR-7074-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7074-5p antagomir mmu-miR-7074-5p antagomir

HY-RI03893

*mmu-miR-7074-3p inhibitor*	MicroRNA	Cancer
mmu-miR-7074-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-7074-3p inhibitor mmu-miR-7074-3p inhibitor

HY-RI03893A

*mmu-miR-7074-3p antagomir*	MicroRNA	Cancer
mmu-miR-7074-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7074-3p antagomir mmu-miR-7074-3p antagomir

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P702649

	PKN2 Protein, Human (Active, sf9, His, GST) PKN2; protein kinase N2; PRKCL2, protein kinase C like 2; serine/threonine-protein kinase N2; cardiolipin activated protein kinase Pak2; Pak 2; PRK2; PKN gamma; protein kinase C-like 2; protein-kinase C-related kinase 2; cardiolipin-activated protein kinase Pak2; PAK2; Pak-2; PRKCL2; PRO2042; MGC71074; MGC150606	Human	Sf9 insect cells
	PKN2 Protein, Human (sf9, His, GST) is the recombinant human-derived PKN2, expressed by Sf9 insect cells , with His, GST labeled tag. ,

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Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Mouse (9) Rabbit (1)
Reactivity:	Human (9) mouse (1) Rat (6) Mouse (6) rat (1) Monkey (2) human (1)
Application:	IHC-P (8) ICC/IF (2) IF-Tissue (1) IP (1) WB (7) FC (2) ELISA (3)
Isotype:	IgG (1) IgG1 (7) IgG2a (2)
Conjugation:	Non-conjugated (10)
Clonality:	Monoclonal (5) Recombinant (1)
Modification:	Unmodified (6)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P89730

	BLVRA Antibody (YA9074)	WB, ICC/IF, IF-Tissue, IP, ELISA	human, mouse, rat
	BLVRA Antibody (YA9074) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to BLVRA.

HY-P88220

	NR4A3 Antibody (YA7904) CHN; CSMF; MINOR; NOR1	WB, IHC-P	Human, Mouse, Rat
	NR4A3 Antibody (YA7904) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NR4A3.

HY-P88290

	CDCA7L Antibody (YA7974) JPO2; R1; RAM2	IHC-P	Human
	CDCA7L Antibody (YA7974) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CDCA7L.

HY-P88220A

	NR4A3 Antibody (YA7904)(PBS only) CHN; CSMF; MINOR; NOR1	IHC-P	Human, Mouse, Rat
	NR4A3 Antibody (YA7904) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NR4A3.

HY-P88290A

	CDCA7L Antibody (YA7974)(PBS only) JPO2; R1; RAM2	IHC-P	Human
	CDCA7L Antibody (YA7974) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CDCA7L.

HY-P84612

	PRK2 Antibody (YA4309) PKN2; PAK2; PRK2; Pak-2; PRKCL2; PRO2042; MGC71074; MGC150606	WB, IHC-P, FC, ELISA	Human, Mouse, Rat, Monkey
	PRK2 Antibody (YA4309) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRK2.

HY-P84612A

	PRK2 Antibody (YA4309)(PBS only) PKN2; PAK2; PRK2; Pak-2; PRKCL2; PRO2042; MGC71074; MGC150606	WB, IHC-P, FC, ELISA	Human, Mouse, Rat, Monkey
	PRK2 Antibody (YA4309) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRK2.

HY-P88223

	GIPC1 Antibody (YA7907) C19orf3; GIPC; GLUT1CBP; Hs.6454; IIP-1; NIP; RGS19IP1; SEMCAP; SYNECTIIN; SYNECTIN; TIP-2	WB, IHC-P	Human, Mouse, Rat
	GIPC1 Antibody (YA7907) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GIPC1.

HY-P88223A

	GIPC1 Antibody (YA7907)(PBS only) C19orf3; GIPC; GLUT1CBP; Hs.6454; IIP-1; NIP; RGS19IP1; SEMCAP; SYNECTIIN; SYNECTIN; TIP-2	WB, IHC-P	Human, Mouse, Rat
	GIPC1 Antibody (YA7907) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GIPC1.

HY-P87391

	SCXA Antibody (YA7074) Basic helix loop helix transcription factor scleraxis antibody; Basic helix-loop-helix transcription factor scleraxis antibody; bHLHa41 antibody; bHLHa48 antibody; Class A basic helix-loop-helix protein 41 antibody; Class A basic helix-loop-helix protein 48 antibody; scleraxis antibody; scleraxis homolog A antibody; SCX antibody; SCX_HUMAN antibody	WB, ICC/IF	Human
	SCXA Antibody (YA7074) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SCXA.

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Products	In-stock - + Add to Cart
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Host
Reactivity
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Clonality
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SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-R02438

*hsa-miR-7974* mimic**		MicroRNAs miRNA mimics
hsa-miR-7974 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI02438

*hsa-miR-7974* inhibitor**		MicroRNAs miRNA inhibitors
hsa-miR-7974 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03893

*mmu-miR-7074-3p mimic*		MicroRNAs miRNA mimics
mmu-miR-7074-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R02438A

*hsa-miR-7974* agomir**		MicroRNAs miRNA agomirs
hsa-miR-7974 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI02438A

*hsa-miR-7974* antagomir**		MicroRNAs miRNA antagomirs
hsa-miR-7974 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03894

*mmu-miR-7074-5p inhibitor*		MicroRNAs miRNA inhibitors
mmu-miR-7074-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03894A

*mmu-miR-7074-5p agomir*		MicroRNAs miRNA agomirs
mmu-miR-7074-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03894

*mmu-miR-7074-5p mimic*		MicroRNAs miRNA mimics
mmu-miR-7074-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03893A

*mmu-miR-7074-3p agomir*		MicroRNAs miRNA agomirs
mmu-miR-7074-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03894A

*mmu-miR-7074-5p antagomir*		MicroRNAs miRNA antagomirs
mmu-miR-7074-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03893

*mmu-miR-7074-3p inhibitor*		MicroRNAs miRNA inhibitors
mmu-miR-7074-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03893A

*mmu-miR-7074-3p antagomir*		MicroRNAs miRNA antagomirs
mmu-miR-7074-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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