TSLIG2 - tRNA splicing ligase complex subunit 2 Gene
Also Known as asw; C2orf49
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 79074
Summary
Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Located in nucleoplasm. Part of tRNA-splicing Ligase complex. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in ovary (RPKM 7.4), endometrium (RPKM 6.7) and 25 other tissues.
TSLIG2 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001286537.2 | NP_001273466.1 | tRNA-splicing ligase complex subunit ASW isoform 2 |
| NM_024093.3 | NP_076998.1 | tRNA-splicing ligase complex subunit ASW isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
30021884 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
18445686 | GOA |
| part of tRNA-splicing ligase complex |
IDA
IDA: Inferred from direct assay
|
21311021 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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TSLIG2 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
C2orf49 | Q9BVC5 | RTRAF | Homo sapiens | Q9Y224 | 33961781 | |
|
Intra
|
C2orf49 | Q9BVC5 | WFS1 | Homo sapiens | O76024 | 32814053 | |
|
Intra
|
C2orf49 | Q9BVC5 | WFS1 | Homo sapiens | O76024 | 32814053 | |
|
Intra
|
C2orf49 | Q9BVC5 | WFS1 | Homo sapiens | O76024 | 32814053 |
Cross: Cross-species interaction
Intra: Intraspecies interaction