1. GPCR/G Protein
  2. Glucagon Receptor
  3. PF-06291874

PF-06291874 (Synonyms: Glucagon receptor antagonists-4)

Cat. No.: HY-19947 Purity: 99.70%
Handling Instructions

PF-06291874 is a highly potent glucagon receptor antagonist. It displays low in vivo clearance and excellent oral bioavailability in both rats and dogs.

For research use only. We do not sell to patients.

PF-06291874 Chemical Structure

PF-06291874 Chemical Structure

CAS No. : 1393124-08-7

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 465 In-stock
Estimated Time of Arrival: December 31
1 mg USD 180 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2520 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

PF-06291874 is a highly potent glucagon receptor antagonist. It displays low in vivo clearance and excellent oral bioavailability in both rats and dogs.

Clinical Trial
Molecular Weight

503.51

Formula

C₂₆H₂₈F₃N₃O₄

CAS No.

1393124-08-7

SMILES

CCC[[email protected]](OC1=CC(C)=C(N2C=C(C(F)(F)F)C=N2)C(C)=C1)C3=CC=C(C(NCCC(O)=O)=O)C=C3

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (59.58 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9861 mL 9.9303 mL 19.8606 mL
5 mM 0.3972 mL 1.9861 mL 3.9721 mL
10 mM 0.1986 mL 0.9930 mL 1.9861 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
PF-06291874
Cat. No.:
HY-19947
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