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Cat. No.: HY-N13282

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Glyceocarpin

Glyceocarpin is a phytoalexin and antibacterial agent naturally occurring in Glycine max, with weak antifungal activity. Glyceocarpin serves as the biosynthetic precursor of Glyceollins II (HY-N18032) and Glyceollins III. Glyceocarpin can be biosynthesized by the prenyltransferase and subsequent modification by cytochrome P450 enzymes. Glyceocarpin can be used for the study of soybean root and stem rot caused by Phytophthora sojae.

For research use only. We do not sell to patients.

CAS No.: 77979-22-7
Formula: C₂₀H₂₀O₅
Molecular Weight:340.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Glyceocarpin Chemical Structure

CAS No.: 77979-22-7

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

In Vitro

Glyceocarpin can be oxidatively cyclized into Glyceollin II and Glyceollin III by GmGIIS and GmGIIIS respectively in both Nicotiana benthamiana leaves and Saccharomyces cerevisiae WAT11 cells^[1].
Glyceocarpin serves as a key precursor for the de novo biosynthesis of Glyceollin II and Glyceollin III in engineered yeast strains^[1].
Glyceocarpin (25 μg) exhibits antibacterial activity against Pseudomonas pisi^[2].
Glyceocarpin (30 μg) shows weak antifungal activity against Cladosporium cucumerinum^[2].
Glyceocarpin (1 mg/mL; 48 hours) accumulates in elicitor-treated soybean cotyledons^[2].
Glyceocarpin specifically serves as a substrate for soybean CYP82A subfamily enzymes (CYP82A4, CYP82A4b, CYP82A2, CYP82A24) to produce Glyceollin II, Glyceollin III, or a mixture of Glyceofuran, 13-epi-glyceollin III, and Glyceollin VII, respectively^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 77979-22-7
Molecular Weight 340.38
Formula C₂₀H₂₀O₅
SMILES

O[C@]12[C@](C=3C(OC1)=CC(O)=C(CC=C(C)C)C3)(OC=4C2=CC=C(O)C4)[H]
Structure Classification
- Phenols
- Polyphenols
- Others
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sun Y, et al. Elucidation and de novo reconstitution of glyceollin biosynthesis. Mol Plant. 2025;18(5):820-832. [Content Brief]

[2]. Ingham JL, et al. Inducibly-formed isoflavonoids from leaves of soybean. Phytochemistry. 1981;20(5):1117-1121.

[3]. Raytek LM, et al. At the roots of resistance. Nat Chem Biol. 2025 Jun 26;21:1473–1475.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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