GZ-11608
GZ-11608 is a potent and selective vesicular monoamine transporter-2 (VMAT2) inhibitor with high affinity (Ki = 25 nM). GZ-11608 decreases methamphetamine-induced dopamine release from isolated synaptic vesicles from brain dopaminergic neurons. GZ-11608 exhibits rapid brain penetration and without neurotoxicity. GZ-11608 can be used for the research of methamphetamine use disorder.
For research use only. We do not sell to patients.
- CAS No.: 2141974-01-6
- Formula: C19H25NO
- Molecular Weight:283.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Ki: 25 nM (VMAT2)[1]
Chemical Information
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CAS No. 2141974-01-6
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Molecular Weight 283.41
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Formula C19H25NO
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SMILES
C[C@H](NCCCC1=CC=C(OC)C=C1)CC2=CC=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)