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hsa-miR-4432 agomir

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Based on 1 publication(s) in Google Scholar

hsa-miR-4432 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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  • Molecular Weight:13789.56
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • hsa-miR-4432 agomir Chemical Structure
    hsa-miR-4432 agomir Chemical Structure
  • Experimental Validation Results for hsa-miR-4432 agomir
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  • hsa-miR-4432 agomir Chemical Structure
    hsa-miR-4432 agomir Chemical Structure RNA, (AAAGACUCUGCAAGAUGCCU), complex with RNA, (GCAUCUUGCAGAGUCUUUNN) (1:1) (with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification)
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    hsa-miR-4432 agomir purchased from MedChemExpress. Usage Cited in: Biology (Basel). 2023 Mar 16;12(3):459. [Abstract]

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     miR-4432 mimic significantly reduces the mitochondrial oxidative stress in hBMECs.

  • RNA, (AAAGACUCUGCAAGAUGCCU), complex with RNA, (GCAUCUUGCAGAGUCUUUNN) (1:1) (with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification)