Antimalarial agent 54
Antimalarial agent 54 (Compound 23) is a potent antimalarial agent that mainly kills the late-stage trophozoites of the malaria parasite. Antimalarial agent 54 can inhibit the formation of hemozoin in the malaria parasite, resulting in the accumulation of free hemoglobin within the malaria parasite. Antimalarial agent 54 shows IC50 values of 0.14 and 0.19 μM against P. falciparum NF54 and Dd2 parasite. Antimalarial agent 54 can be used for research of malaria.
For research use only. We do not sell to patients.
- Formula: C20H17ClN4O
- Molecular Weight:364.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Antimalarial agent 54 shows an IC50 of 21 μM for CHO cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 364.83
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Formula C20H17ClN4O
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SMILES
ClC(C=C1)=CC=C1NC(C2=CC(/C=C/C3=CC(C)=CN=C3N)=CN=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)