Tizoxanide-d4 glucuronide
Tizoxanide-d4 glucuronide is the deuterium labeled Tizoxanide glucuronide. Tizoxanide glucuronide is the metabolite of Nitazoxanide (HY-B0217) and is cell-permeable to inhibit asexual and sexual stages development of parasite C. parvum.
For research use only. We do not sell to patients.
- Formula: C16H11D4N3O10S
- Molecular Weight:445.39
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Parasite Isoforms
More
Biological Activity
IC50: parasite[1]
Tizoxanide glucuronide (1-50 μg/ml; 46 hours) has effects on parasite development of Cryptosporidium parvum in HCT-8 cells. It exhibits MIC50 values of 2.2 μg/ml; 45.2 μg/ml; 11.7 μg/ml and 2.8 μg/ml in a sexual and sexual stages, sporozoite stage, asexual stages and sexual stages, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Molecular Weight 445.39
-
Formula C16H11D4N3O10S
-
SMILES
O=C(NC1=NC=C([N+]([O-])=O)S1)C2=C(O[C@H]3O[C@@H](C(O)=O)[C@H](O)[C@@H](O)[C@H]3O)C([2H])=C([2H])C([2H])=C2[2H]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz