ETP-45835
ETP-45835 is slective and potent MNK inhibitor with IC50s of 575 nM and 646 nM for MNK1 and MNK2, respectively. ETP-45835 shows little activity against 24 other kinases. ETP-45835 inhibits eIF4E Ser209 phosphorylation in cells, and has anticancer effects.
For research use only. We do not sell to patients.
- CAS No.: 794510-70-6
- Formula: C13H16N4
- Molecular Weight:228.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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MNK1 575 nM (IC50) |
MNK2 646 nM (IC50) |
Chemical Information
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CAS No. 794510-70-6
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Molecular Weight 228.29
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Formula C13H16N4
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SMILES
N=1C=CC(=CC1)C2=NNC(=C2)C3CCNCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)