HPPD-IN-12
HPPD-IN-12 is an inhibitor of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenase (AtHPPD), with an IC50 of 27.8 μM and a Kd of 1.535 μM. HPPD-IN-12 binds to AtHPPD via Fe2+ coordination, π-π interactions and hydrogen bonds. HPPD-IN-12 can be used in herbicide-related research.
For research use only. We do not sell to patients.
- CAS No.: 3124322-98-8
- Formula: C21H24N4O6
- Molecular Weight:428.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
HPPD-IN-12 (compound B18) inhibits AtHPPD with an IC50 of 27.8 μM; its dissociation constant is 1.535 μM, and it exhibits stronger affinity than Bentazone (HY-B2039)[1].
HPPD-IN-12 (0-22 μM) binds to AtHPPD with an association constant of 1.0 × 104.157 M-1, and its affinity is stronger than that of Topramezone (HY-144900)[1].
HPPD-IN-12 stably binds to AtHPPD[1] through Fe2+ chelation, π-π stacking, and hydrogen bonding interactions with amino acid residues at key active sites.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3124322-98-8
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Molecular Weight 428.44
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Formula C21H24N4O6
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SMILES
CCOC(OC(C)OC(N(C)N=C1C)=C1C(C2=CC=C(N=C(C)C(N3C)=O)C3=C2)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HPPD-IN-12 Related Classifications
HY-187378 Related Classifications
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