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製品番号: HY-181935

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Antibiotic adjuvant 4

Antibiotic adjuvant 4 (Compound 13) is an Antibiotic adjuvant and efflux pump inhibitor. Antibiotic adjuvant 4 exhibits potent efflux pump inhibitory activity. Antibiotic adjuvant 4 significantly downregulates virulence-related genes of Staphylococcus aureus when used alone or in combination with antibiotics. Antibiotic adjuvant 4 enhances the efficacy of Ciprofloxacin (HY-B0356) against multiagent-resistant Staphylococcus aureus strains.

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CAS 番号: 2493985-50-3
分子式: C₂₁H₃₆O₂
分子量:320.51

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Antibiotic adjuvant 4 構造式

CAS 番号: 2493985-50-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Antibiotic adjuvant 4 (1.56-50 μM; 20 h) sensitizes multiagent-resistant Staphylococcus aureus SA4 to ciprofloxacin, reducing the MIC of Ciprofloxacin from 94.84 μM when used alone to 17.12 μM when used in combination with ciprofloxacin^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2493985-50-3
分子量 320.51
分子式 C₂₁H₃₆O₂
SMILES

C[C@@]12[C@@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CCC4)([H])C[C@H](OCCO)CC1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Brdová D, et al. Steroidal hormones and neurosteroids - novel therapeutic strategies in bacterial infections: Design, synthesis, and biological evaluation. Eur J Med Chem. 2026;308:118716. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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