Antimalarial agent 54
Antimalarial agent 54 (Compound 23) is a potent antimalarial agent that mainly kills the late-stage trophozoites of the malaria parasite. Antimalarial agent 54 can inhibit the formation of hemozoin in the malaria parasite, resulting in the accumulation of free hemoglobin within the malaria parasite. Antimalarial agent 54 shows IC50 values of 0.14 and 0.19 μM against P. falciparum NF54 and Dd2 parasite. Antimalarial agent 54 can be used for research of malaria.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C20H17ClN4O
- 分子量:364.83
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Antimalarial agent 54 shows an IC50 of 21 μM for CHO cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 364.83
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分子式 C20H17ClN4O
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SMILES
ClC(C=C1)=CC=C1NC(C2=CC(/C=C/C3=CC(C)=CN=C3N)=CN=C2)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)