BB-Cl-Amidine TFA
Based on 11 publication(s) in Google Scholar
BB-Cl-Amidine TFA is a peptidylarginine deminase (PAD) inhibitor.
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- 分子式: C28H27ClF3N5O3
- 分子量:573.99
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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MedChemExpress（MCE）の使用を引用している文献 BB-Cl-Amidine TFA
More- Nat Cell Biol. 2021 Oct;23(10):1060-1072. [Abstract]
- Nat Commun. 2024 Sep 3;15(1):7654. [Abstract]
- Adv Sci (Weinh). 2025 Aug 20:e11873. [Abstract]
- Mol Med. 2025 Feb 5;31(1):46. [Abstract]
- Acta Neuropathol Commun. 2025 Feb 18;13(1):33. [Abstract]
- Int Immunopharmacol. 2024 Nov 5;143(Pt 3):113534. [Abstract]
- Oncol Rep. 2023 Jul;50(1):146. [Abstract]
- J Antibiot (Tokyo). 2025 Oct 9. [Abstract]
- Cell Physiol Biochem. 2024 Feb 19;58(1):63-82. [Abstract]
- bioRxiv. 2026 Jan 21:2026.01.20.700682. [Abstract]
- Res Sq. 2024 Jun 04.
生物活性
化学情報
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分子量 573.99
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分子式 C28H27ClF3N5O3
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SMILES
O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C3=NC4=C(N3)C=CC=C4)CCCNC(CCl)=N.OC(C(F)(F)F)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (11)
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Journal Impact Factor
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Most Recent
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Nat Cell Biol
2021 Oct;23(10):1060-1072. PMID: 34616019 -
Nat Commun
2024 Sep 3;15(1):7654. PMID: 39227578 -
Adv Sci (Weinh)
Succinate Dehydrogenase Subunit A (SDHA) Mediated Microglia Extracellular Traps Formation Participating in Cerebral Ischemic Reperfusion Injury. [Abstract]2025 Aug 20:e11873. PMID: 40832885 -
Mol Med
Platelet-derived HMGB1 induces NETosis, exacerbating brain damage in the photothrombotic stroke model. [Abstract]2025 Feb 5;31(1):46. PMID: 39910417 -
Acta Neuropathol Commun
Blocking peptidyl arginine deiminase 4 confers neuroprotective effect in the post-ischemic brain through both NETosis-dependent and -independent mechanisms. [Abstract]2025 Feb 18;13(1):33. PMID: 39966968 -
Int Immunopharmacol
HSYA ameliorates venous thromboembolism by depleting the formation of TLR4/NF-κB pathway-dependent neutrophil extracellular traps. [Abstract]2024 Nov 5;143(Pt 3):113534. PMID: 39504860 -
Oncol Rep
Inhibition of protein arginine deiminase II suppresses retinoblastoma in orthotopic transplantation in mice. [Abstract]2023 Jul;50(1):146. PMID: 37326108 -
J Antibiot (Tokyo)
Antibacterial effects of BB-Cl-Amidine against multidrug-resistant Gram-positive pathogens via membrane disruption. [Abstract]2025 Oct 9. PMID: 41068498 -
Cell Physiol Biochem
Peptidylarginine Deiminases Inhibitors Decrease Endothelial Cells Angiogenic Potential by Affecting Akt Signaling and the Expression and Secretion of Angiogenic Factors. [Abstract]2024 Feb 19;58(1):63-82. PMID: 38374715 -
bioRxiv
Reciprocal regulation between the protein arginine deiminases and mSWI/SNF chromatin remodelers controls skeletal muscle differentiation and regeneration. [Abstract]2026 Jan 21:2026.01.20.700682. PMID: 41659480 -
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
BB-Cl-Amidine TFA 関連分類
HY-111347B 関連分類
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