アゾルビン
Based on 1 Customer Validation
Carmoisine (Azorubine) is an azo dye that can be used as a food additive.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.66%
- CAS 番号: 3567-69-9
- 分子式: C20H12N2Na2O7S2
- 分子量:502.43
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Carmoisine augments the in vitro synthesis of leukotriene B4 (LTB4) and F2-isoprostanes from blood neutrophils. Carmoisine increases the formation of F2-isoprostanes from blood neutrophils at all tested concentrations[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Wistar rats (120-300 g)[1]
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Dosage:49.3 mg/kg, 493 mg/kg
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Administration:Oral administration; for 42 days
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Result:Resulted in apoptosis according to MAPK8 expression.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 3567-69-9
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性状 Solid
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分子量 502.43
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分子式 C20H12N2Na2O7S2
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Color Brown to black
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SMILES
O=S(C1=C2C=CC=CC2=C(O)C(/N=N/C3=C4C=CC=CC4=C(S(=O)(O[Na])=O)C=C3)=C1)(O[Na])=O
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別名
Carmoisine; Azorubine; Acid Red 14; E122
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
DMSO : 50 mg/mL (99.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. B Raposa, et al. Food additives: Sodium benzoate, potassium sorbate, azorubine, and tartrazine modify the expression of NFκB, GADD45α, and MAPK8 genes. Physiol Int. 2016 Sep;103(3):334-343. [Content Brief]
[2]. Latasha Leo, et al. Occurrence of azo food dyes and their effects on cellular inflammatory responses. Nutrition. 2018 Feb;46:36-40. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9903 mL | 9.9516 mL | 19.9033 mL | 49.7582 mL |
| 5 mM | 0.3981 mL | 1.9903 mL | 3.9807 mL | 9.9516 mL | |
| 10 mM | 0.1990 mL | 0.9952 mL | 1.9903 mL | 4.9758 mL | |
| 15 mM | 0.1327 mL | 0.6634 mL | 1.3269 mL | 3.3172 mL | |
| 20 mM | 0.0995 mL | 0.4976 mL | 0.9952 mL | 2.4879 mL | |
| 25 mM | 0.0796 mL | 0.3981 mL | 0.7961 mL | 1.9903 mL | |
| 30 mM | 0.0663 mL | 0.3317 mL | 0.6634 mL | 1.6586 mL | |
| 40 mM | 0.0498 mL | 0.2488 mL | 0.4976 mL | 1.2440 mL | |
| 50 mM | 0.0398 mL | 0.1990 mL | 0.3981 mL | 0.9952 mL | |
| 60 mM | 0.0332 mL | 0.1659 mL | 0.3317 mL | 0.8293 mL | |
| 80 mM | 0.0249 mL | 0.1244 mL | 0.2488 mL | 0.6220 mL |
Carmoisine 関連分類
HY-128448 関連分類
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