(E)-Selinexor
Based on 1 Customer Validation
(E)-Selinexor ((E)-KPT-330) is the E-isomer of Selinexor (HY-17536). Selinexor is the selective, orally active CRM1 inhibitor.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.0%
- CAS 番号: 1421923-86-5
- 分子式: C17H11F6N7O
- 分子量:443.31
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Membrane Transporter/Ion Channel Compound Library
HY-L011
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FDA-Approved Drug Library
HY-L022
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Anti-Cancer Compound Library
HY-L025
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Drug Repurposing Compound Library
HY-L035
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FDA Approved & Pharmacopeial Drug Library
HY-L066
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FDA-Approved Anticancer Drug Library
HY-L122
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Drug Repurposing Compound Library Plus
HY-L035P
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FDA-Approved Drug Library Plus
HY-L022P
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FDA-Approved Drug Library Mini
HY-L022M
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | CC50 |
>20 μM
Compound: MMV1593517
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Cytotoxicity against HEK293 cells (CO-ADD:MA_007); CC50 by cell viability assay in DMEM (10% FBS) media using TC plates, by Resazurin F(560/590)
Cytotoxicity against HEK293 cells (CO-ADD:MA_007); CC50 by cell viability assay in DMEM (10% FBS) media using TC plates, by Resazurin F(560/590)
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10.6019/CHEMBL4296181 |
化学情報
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CAS 番号 1421923-86-5
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性状 Solid
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分子量 443.31
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分子式 C17H11F6N7O
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Color Off-white to light yellow
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SMILES
O=C(NNC1=NC=CN=C1)/C=C/N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
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別名
(E)-KPT-330
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (112.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2558 mL | 11.2788 mL | 22.5576 mL | 56.3939 mL |
| 5 mM | 0.4512 mL | 2.2558 mL | 4.5115 mL | 11.2788 mL | |
| 10 mM | 0.2256 mL | 1.1279 mL | 2.2558 mL | 5.6394 mL | |
| 15 mM | 0.1504 mL | 0.7519 mL | 1.5038 mL | 3.7596 mL | |
| 20 mM | 0.1128 mL | 0.5639 mL | 1.1279 mL | 2.8197 mL | |
| 25 mM | 0.0902 mL | 0.4512 mL | 0.9023 mL | 2.2558 mL | |
| 30 mM | 0.0752 mL | 0.3760 mL | 0.7519 mL | 1.8798 mL | |
| 40 mM | 0.0564 mL | 0.2820 mL | 0.5639 mL | 1.4098 mL | |
| 50 mM | 0.0451 mL | 0.2256 mL | 0.4512 mL | 1.1279 mL | |
| 60 mM | 0.0376 mL | 0.1880 mL | 0.3760 mL | 0.9399 mL | |
| 80 mM | 0.0282 mL | 0.1410 mL | 0.2820 mL | 0.7049 mL | |
| 100 mM | 0.0226 mL | 0.1128 mL | 0.2256 mL | 0.5639 mL |
(E)-Selinexor 関連分類
HY-17536A 関連分類
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