BBS4 - Bardet-Biedl syndrome 4 Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 585

About BBS4

Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:72,686,207-72,738,473 (from NCBI)

This gene has 18 transcripts (splice variants), 210 orthologues, 14 paralogues and is associated with 3 phenotypes. Ubiquitous expression in testis (RPKM 12.7), prostate (RPKM 9.9) and 25 other tissues.

Summary

This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in Plants and archaebacteria and in human forms a multi-protein "BBSome" complex with seven Other BBS proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

BBS4 Products (3)

mRNA	Protein	Name
NM_001252678.2	NP_001239607.1	Bardet-Biedl syndrome 4 protein isoform 2
NM_001320665.2	NP_001307594.1	Bardet-Biedl syndrome 4 protein isoform 3
NM_033028.5	NP_149017.2	Bardet-Biedl syndrome 4 protein isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	参考文献	由来
enables RNA polymerase II-specific DNA-binding transcription factor binding	IPI IPI: Inferred from physical interaction	22302990	GOA
enables alpha-tubulin binding	IDA IDA: Inferred from direct assay	17574030	GOA
enables beta-tubulin binding	IDA IDA: Inferred from direct assay	17574030	GOA
enables dynactin binding	IDA IDA: Inferred from direct assay	15107855	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	15107855	GOA
enables protein-macromolecule adaptor activity	IMP IMP: Inferred from mutant phenotype	15107855	GOA

Biological Process GO Annotation	Evidence	参考文献	由来
involved in centrosome cycle	IMP IMP: Inferred from mutant phenotype	15107855	GOA
involved in maintenance of protein location in nucleus	IGI IGI: Inferred from genetic interaction	15107855	GOA
involved in microtubule anchoring at centrosome	IMP IMP: Inferred from mutant phenotype	15107855	GOA
involved in mitotic cytokinesis	IMP IMP: Inferred from mutant phenotype	15107855	GOA
involved in protein localization to centrosome	IMP IMP: Inferred from mutant phenotype	15107855	GOA
involved in protein localization to cilium	IMP IMP: Inferred from mutant phenotype	23943788	GOA
involved in regulation of cytokinesis	IMP IMP: Inferred from mutant phenotype	15107855	GOA

Cellular Component GO Annotation	Evidence	参考文献	由来
part of BBSome	IDA IDA: Inferred from direct assay	17574030	GOA
part of BBSome	IPI IPI: Inferred from physical interaction	19081074	GOA
located in centriolar satellite	IDA IDA: Inferred from direct assay	15107855	GOA
located in centriole	IDA IDA: Inferred from direct assay	15107855	GOA
located in centrosome	IDA IDA: Inferred from direct assay	14520415	GOA
located in ciliary basal body	IDA IDA: Inferred from direct assay	15107855	GOA
located in ciliary membrane	IDA IDA: Inferred from direct assay	17574030	GOA
located in ciliary transition zone	IDA IDA: Inferred from direct assay	23943788	GOA
located in cilium	IDA IDA: Inferred from direct assay	23943788	GOA
located in motile cilium	IDA IDA: Inferred from direct assay	18299575	GOA
located in non-motile cilium	IDA IDA: Inferred from direct assay	17574030	GOA
located in pericentriolar material	IDA IDA: Inferred from direct assay	15107855	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BBS4 Protein Structure

TPR_11

TPR_8

0
100
200
300
400
519 a.a.

Protein Preferred Names	Protein Names
Bardet-Biedl syndrome 4 protein

BBS4 Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	BBS4	Q96RK4	REL	Homo sapiens	Q04864-2	Validated Y2H	26871637
Intra	BBS4	Q96RK4	REL	Homo sapiens	Q04864-2	Y2H Array	26871637
Intra	BBS4	Q96RK4	REL	Homo sapiens	Q04864-2	Y2H Prey Pooling	26871637
Intra	BBS4	Q96RK4	PLP1	Homo sapiens	P60201-2	Validated Y2H	32814053
Intra	BBS4	Q96RK4	PLP1	Homo sapiens	P60201-2	Y2H Pooling	32814053
Intra	BBS4	Q96RK4	PLP1	Homo sapiens	P60201-2	Y2H Array	32814053
Intra	BBS4	Q96RK4	BBS1	Homo sapiens	Q8NFJ9	TAP	27173435
Intra	BBS4	Q96RK4	BBS1	Homo sapiens	Q8NFJ9	TAP	19081074
Intra	BBS4	Q96RK4	BBS1	Homo sapiens	Q8NFJ9	Anti Tag CoIP	17574030
Intra	BBS4	Q96RK4	BBS1	Homo sapiens	Q8NFJ9	TAP	17574030
Intra	BBS4	Q96RK4	IQCB1	Homo sapiens	Q15051	IF	25552655
Intra	BBS4	Q96RK4	BBS9	Homo sapiens	Q3SYG4	TAP	27173435
Intra	BBS4	Q96RK4	BBS9	Homo sapiens	Q3SYG4	TAP	17574030
Intra	BBS4	Q96RK4	BBS9	Homo sapiens	Q3SYG4	TAP	19081074
Intra	BBS4	Q96RK4	BBIP1	Homo sapiens	A8MTZ0	Lumier	29039417
Intra	BBS4	Q96RK4	BBIP1	Homo sapiens	A8MTZ0	Y2H	29039417
Intra	BBS4	Q96RK4	BBIP1	Homo sapiens	A8MTZ0	TAP	19081074
Intra	BBS4	Q96RK4	BBIP1	Homo sapiens	A8MTZ0	IF	19081074
Intra	BBS4	Q96RK4	BBIP1	Homo sapiens	A8MTZ0	GMS	19081074
Intra	BBS4	Q96RK4	MYOG	Homo sapiens	P15173	Validated Y2H	25416956
Intra	BBS4	Q96RK4	P4HB	Homo sapiens	P07237	Y2H Array	32814053
Intra	BBS4	Q96RK4	P4HB	Homo sapiens	P07237	Y2H Pooling	32814053
Intra	BBS4	Q96RK4	P4HB	Homo sapiens	P07237	Validated Y2H	32814053
Intra	BBS4	Q96RK4	EPAS1	Homo sapiens	Q99814	CoIP	18000879
Intra	BBS4	Q96RK4	DCTN1	Homo sapiens	Q14203	Anti Tag CoIP	15107855
Intra	BBS4	Q96RK4	PCM1	Homo sapiens	Q15154	Anti Tag CoIP	17574030
Intra	BBS4	Q96RK4	PCM1	Homo sapiens	Q15154	TAP	17574030
Intra	BBS4	Q96RK4	PCM1	Homo sapiens	Q15154	Anti Tag CoIP	15107855
Intra	BBS4	Q96RK4	PCM1	Homo sapiens	Q15154	TAP	19081074
Intra	BBS4	Q96RK4	PCM1	Homo sapiens	Q15154	Confocal	15107855
Intra	BBS4	Q96RK4	PCM1	Homo sapiens	Q15154	Y2H	15107855
Intra	BBS4	Q96RK4	PCM1	Homo sapiens	Q15154	Anti Tag CoIP	22500027
Intra	BBS4	Q96RK4	PCM1	Homo sapiens	Q15154	Y2H	18000879
Intra	BBS4	Q96RK4	PCM1	Homo sapiens	Q15154	Cosedimentation	18772192

Cross: Cross-species interaction Intra: Intraspecies interaction

BBS4 抗体

製品番号	製品名	アプリケーション	反応性
HY-P810831	BBS4 Antibody (YA10074)	WB	Human, Mouse, Rat

関連疾患

Diseases	Alias
Bardet-Biedl Syndrome 4	BBS4 Bardet-Biedl Syndrome, Type 4
Bardet-Biedl Syndrome	Bbs Biedl-Bardet Syndrome
Cone-Rod Dystrophy 2	Cone-Rod Dystrophy CORD2 Cone-Rod Retinal Dystrophy Rcrd2 Cone-Rod Retinal Dystrophy 2 Crd2 Cord Crd Retinal Cone-Rod Dystrophy Cone-Rod Retinal Dystrophy-2 Retinal Cone-Rod Dystrophy 2 Tapetoretinal Degeneration Cone-Rod Degeneration Cone Rod Dystrophy Dystrophy, Cone-Rod Dystrophy, Cone-Rod, Type 2 Retinitis Pigmentosa Retinitis Pigmentosa 2 Progressive Cone-Rod Dystrophy
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1
Polydactyly	Non-Syndromic Polydactyly Polydactyly, Postaxial Postaxial Polydactyly Supernumerary Digit Extra Digits Hyperdactyly Polydactylia Polydactylism Supernumerary Digits
Mckusick-Kaufman Syndrome	MKKS Hydrometrocolpos, Postaxial Polydactyly, And Congenital Heart Malformation Hmcs Kaufman-Mckusick Syndrome Hydrometrocolpos Syndrome Hydrometrocolpos-Postaxial Polydactyly Syndrome Kaufman Mckusick Syndrome Mckusick Kaufman Syndrome Mks
Developmental And Epileptic Encephalopathy 43	DEE43 Epileptic Encephalopathy, Early Infantile, 43 Eiee43 Developmental And Epileptic Encephalopathy, 43 Early Infantile Epileptic Encephalopathy 43
Bardet-Biedl Syndrome 18	BBS18 Bardet-Biedl Syndrome, Type 18
Simpson-Golabi-Behmel Syndrome, Type 2	Simpson-Golabi-Behmel Syndrome Type 2 SGBS2 Simpson-Golabi-Behmel Syndrome 2
Fundus Dystrophy	Retinal Dystrophy Retinal Dystrophies Dystrophy, Retinal
Bardet-Biedl Syndrome 11	BBS11 Bardet-Biedl Syndrome Bbs Bardet-Biedl Syndrome, Type 11
Night Blindness, Congenital Stationary, Autosomal Dominant 3	Congenital Stationary Night Blindness Autosomal Dominant 3 CSNBAD3 Night Blindness, Congenital Stationary, Nougaret Type Nougaret Type Congenital Stationary Night Blindness Congenital Stationary Night Blindness Nougaret Type Hemeralopia Congenital Essential Blindness, Night, Stationary, Congenital, Autosomal Dominant, Type 3
Meckel Syndrome, Type 1	Meckel-Gruber Syndrome Meckel Syndrome Dysencephalia Splanchnocystica Meckel Syndrome 1 MKS1 Mks Gruber Syndrome Meckel-Gruber Syndrome, Type 1 Mes Dysencephalia Splachnocystica Meckel Gruber Syndrome Meckel Syndrome Type 1
Joubert Syndrome 26	JBTS26
Retinal Degeneration	Degeneration Of Retina
Bardet-Biedl Syndrome 6	BBS6 Bardet-Biedl Syndrome, Type 6
Bardet-Biedl Syndrome 19	BBS19 Bardet-Biedl Syndrome, Type 19
Orofaciodigital Syndrome I	OFD1 Orofaciodigital Syndrome 1 Oral-Facial-Digital Syndrome, Type I Oral-Facial-Digital Syndrome 1 Ofds I Papillon-Leage And Psaume Syndrome Papillon-Leage-Psaume Syndrome Oral-Facial-Digital Syndrome Type 1 Orofaciodigital Syndrome Type 1 Orofaciodigital Syndromes Orofaciodigital Syndrome Type I Oral-Facial-Digital Syndrome Type I Ofd Syndrome 1 Ofds 1 Oral Facial Digital Syndrome 1 Oral Facial Digital Syndrome Type 1 Papillon-League-Psaume Syndrome Ofdi Ofdsi Orofaciodigital Syndrome, Type I
Orofaciodigital Syndrome	Oral-Facial-Digital Syndrome Orofaciodigital Syndromes Ofd Oral Facial Digital Syndromes Oral-Facial-Digital Syndromes Dysplasia Linguofacialis Ofds Oro-Facio-Digital Syndrome Orodigitofacial Dysostosis Orodigitofacial Syndrome Oral Facial Digital Syndrome Orofaciodigital Syndrome I
Bardet-Biedl Syndrome 10	BBS10 Bardet-Biedl Syndrome Bbs Bardet-Biedl Syndrome, Type 10
Chromosome 2q35 Duplication Syndrome	Syndactyly Syndactyly Type 1 Sdty1 Zygodactyly Syndactyly, Type I Sd1 Syndactyly, Type 1, With Or Without Craniosynostosis Symphalangism Non-Syndromic Syndactyly Symphalangy Webbing Of Digits Syndactyly, Type 1
Bardet-Biedl Syndrome 1	BBS1 Bardet-Biedl Syndrome 1, Modifier Of Bardet-Biedl Syndrome BBS Bardet-Biedl Syndrome, Type 1 Laurence-Moon-Bardet-Biedl Syndrome
Short-Rib Thoracic Dysplasia 3 With Or Without Polydactyly	Asphyxiating Thoracic Dystrophy 3 Saldino-Noonan Syndrome SRTD3 Atd3 Srps1 Srps3 Verma-Naumoff Syndrome Srps2b Short Rib-Polydactyly Syndrome, Verma-Naumoff Type Short Rib-Polydactyly Syndrome, Type I Polydactyly With Neonatal Chondrodystrophy, Type I Polydactyly With Neonatal Chondrodystrophy, Type Iii Short Rib-Polydactyly Syndrome, Type Iib Short Rib-Polydactyly Syndrome Type 3 Polydactyly With Neonatal Chondrodystrophy Type Iii Short Rib-Polydactyly Syndrome Type Iii Short Rib-Polydactyly Syndrome Type 1 Short Rib-Polydactyly Syndrome, Saldino-Noonan Type Majewski Syndrome Short Rib-Polydactyly Syndrome, Type Iii Type I Short Rib Polydactyly Syndrome Srps Type 3 Short Rib Polydactyly Syndrome Verma Naumoff Type Verma Naumoff Syndrome Polydactyly With Neonatal Chondrodystrophy Type 1 Srps Type 1 Short Rib-Polydactyly Syndrome Saldino-Noonan Type Jatd Jeune Asphyxiating Thoracic Dystrophy Jeune Syndrome 3 Polydactyly With Neonatal Chondrodystrophy Type I Short Rib-Polydactyly Syndrome Type I Short Rib-Polydactyly Syndrome Type Iib Srps Type Iib Srps Type Iii
Body Mass Index Quantitative Trait Locus 11	OBESITY Obesity, Susceptibility To Leanness, Inherited Obesity, Susceptibility To, Bmiq11 Obesity, Mild, Early-Onset Obesity, Association With Obesity, Early-Onset, Susceptibility To Obesity, Severe Obesity, Severe, And Type Ii Diabetes Obesity, Late-Onset Obesity , Susceptibility To BMIQ11 Obesity Bmiq11 Obesity, Early-Onset Simple Obesity Nos Excess Fat Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified Adiposis
Acrocallosal Syndrome	ACLS Schinzel Acrocallosal Syndrome Joubert Syndrome 12 Schinzel Syndrome 1 Acrocallosal Syndrome, Schinzel Type Hallux Duplication, Postaxial Polydactyly, And Absence Of Corpus Callosum Acs Absence Of Corpus Callosum With Unusual Facial Appearance, Mental Deficiency, Duplication Of The Halluces And Polydactyly Hallux Duplication Postaxial Polydactyly And Absence Of Corpus Callosum JBTS12 Acrocallosal Syndrome
Senior-Loken Syndrome 1	Senior-Loken Syndrome Renal Dysplasia And Retinal Aplasia Renal-Retinal Syndrome Loken-Senior Syndrome Juvenile Nephronophthisis With Leber Amaurosis SLSN1 Senior-Loken Syndrome-1 Loken Senior Syndrome Senior Loken Syndrome Renal Dysplasia Retinal Aplasia Nephronophthisis With Retinal Dystrophy Renal Dysplasia-Retinal Aplasia Syndrome Slsn
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Heart Malformation Congenital Anomaly Of Heart Heart Defect Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Nephronophthisis	Medullary Cystic Disease Medullary Cystic Kidney Nph Nphp Kidney Disease, Cystic, Medullary
Polycystic Kidney Disease 4 With Or Without Polycystic Liver Disease	Autosomal Recessive Polycystic Kidney Disease Arpkd Polycystic Kidney Disease, Autosomal Recessive Polycystic Kidney And Hepatic Disease 1 Pkhd1 PKD4 Polycystic Kidney Disease 4 With Or Without Hepatic Disease Polycystic Kidney Disease, Infantile, Type I Polycystic Kidney Disease, Infantile Type Polycystic Kidney, Autosomal Recessive Pkd3, Formerly Polycystic Kidney Disease 4, With Or Without Hepatic Disease Arpkd/Chf Ar-Pkd Polycystic Kidney Disease 4, With Or Without Polycystic Liver Disease Infantile Polycystic Kidney Disease Type I Pkd3 Kidney, Polycystic, Disease, Type 4, With/Without Hepatic Disease Polycystic Kidney Disease 3, Autosomal Dominant
Cranioectodermal Dysplasia	Sensenbrenner Syndrome Levin Syndrome 1 Ced Levin Syndrome Dysplasia, Cranioectodermal
Tetralogy Of Fallot	TOF Fallot Tetralogy Ventricular Septal Defect With Pulmonary Stenosis Or Atresia, Dextraposition Of Aorta, And Hypertrophy Of Right Ventricle Tetrad Of Fallot Fallot Tetrad Fallot Disease Fallot Complex Subpulmonic Stenosis, Ventricular Septal Defect, Overriding Aorta, And Right Ventricular Hypertrophy Interventricular Septal Defect With Dextroposition Of Aorta, Pulmonary Stenosis And Hypertrophy Of Right Ventricle Interventricular Septal Defect, In Tetralogy Of Fallot Ventricular Septal Defect With Obstructed Right Ventricular Outflow Tof - [Tetralogy Of Fallot] Pulmonary Atresia With Ventricular Septal Defect [Fallot Type] Pulmonary Atresia, Ventricular Septal Defect And Mapcas Pulmonary Atresia With Ventricular Septal Defect And Systemic-To-Pulmonary Collateral Arteries [Fallot Type]
Cystic Kidney Disease	Renal Cyst Simple Renal Cyst Kidney Cysts Kidney Diseases, Cystic Renal Cysts Kidney Cyst Cystic Kidney Congenital Cystic Kidney Disease Cystic Kidney Diseases Bosniak 1 Cyst
Cone Dystrophy	Retinal Cone Dystrophy Dystrophy, Cone Cone Dystrophy 3
Eye Degenerative Disease
Asphyxiating Thoracic Dystrophy	Jeune Thoracic Dystrophy Jeune Syndrome Asphyxiating Thoracic Dysplasia Short-Rib Thoracic Dysplasia With Or Without Polydactyly Thoracic Pelvic Phalangeal Dystrophy Asphyxiating Thoracic Chondrodystrophy Atd Chondroectodermal Dysplasia-Like Syndrome Infantile Thoracic Dystrophy Jeune Thoracic Dysplasia Thoracic Asphyxiant Dystrophy Thoracic-Pelvic-Phalangeal Dystrophy Short-Rib Thoracic Dysplasia Without Polydactyly Asphyxiating Thoracic Dystrophy Of The Newborn Asphyxiating Thorax Dystrophy
Joubert Syndrome 1	Joubert Syndrome Jbts Cerebellooculorenal Syndrome 1 JBTS1 Joubert-Boltshauser Syndrome Cerebelloparenchymal Disorder Iv Cpd4 Cors1 Joubert Syndrome And Related Disorders Jsrd Familial Aplasia Of The Vermis Joubert Syndrome Related Disorders Js Cerebellar Vermis Agenesis Cerebelloparenchymal Disorder 4 Agenesis Of Cerebellar Vermis Cerebello-Oculo-Renal Syndrome Cors Joubert-Bolthauser Syndrome Cpd Iv Classic Joubert Syndrome Joubert Syndrome Type A Pure Joubert Syndrome Cerebello-Oculo-Renal Syndrome 1 Joubert Syndrome-1 Joubert Syndrome, Type 1 Joubert'S Syndrome
Visceral Heterotaxy	Situs Ambiguus Heterotaxia Heterotaxy Syndrome Heterotaxy Lateralization Defect Situs Ambiguous Left Isomerism Htx Ivemark Syndrome Right Isomerism Situs Ambiguus Viscerum Incomplete Situs Inversus Partial Situs Inversus Heterotaxy, Visceral Asplenia Syndrome Bilateral Left-Sidedness Polysplenia Syndrome Moller Syndrome
Autosomal Dominant Polycystic Kidney Disease	Polycystic Kidney Disease, Adult Type Adpkd Polycystic Kidney Diseases Polycystic Kidney, Autosomal Dominant Congenital Biliary Ectasias Polycystic Kidney And Hepatic Disease 1 Polycystic Kidney Disease, Autosomal Dominant Kidney, Polycystic, Disease, Autosomal Dominant Adult Polycystic Kidney Disease Polycystic Kidney, Adult Type Apckd - [Autosomal Polycystic Kidney Disease]
Situs Inversus	Situs Inversus Viscerum Laterality Sequence Complete Transposition Siv
Polycystic Kidney Disease	Polycystic Kidney Diseases Pkd Polycystic Renal Disease Kidney Disease, Polycystic Polycystic Kidney, Autosomal Dominant
Leber Plus Disease	Leber Congenital Amaurosis Lca Leber'S Amaurosis Leber'S Disease Amaurosis Congenita Of Leber Amaurosis Congenita Of Leber, Type 1 Lhon Plus Disease Congenital Absence Of The Rods And Cones Congenital Retinal Blindness Crb Congenital Amaurosis Of Retinal Origin Leber'S Congenital Amaurosis Leber Congenital Amaurosis 1 Leber'S Congenital Tapetoretinal Degeneration Leber'S Congenital Tapetoretinal Dysplasia Lca1 Leber Congenital Amaurosis Type 1 Retinal Blindness, Congenital Amaurosis, Leber Congenital Dysgenesis Neuroepithelialis Retinae Hereditary Epithelial Dysplasia Of Retina Hereditary Retinal Aplasia Heredoretinopathia Congenitalis Leber Abiotrophy Leber Congenital Tapetoretinal Degeneration Lebers Congenital Amaurosis Optic Atrophy, Hereditary, Leber
Primary Ciliary Dyskinesia	Immotile Cilia Syndrome Kartagener Syndrome Dextrocardia Bronchiectasis And Sinusitis Pcd Ciliary Motility Disorders Ciliary Motility Disorder Immotile Ciliary Syndrome Ciliary Dyskinesia Primary Ics Polynesian Bronchiectasis Dextrocardia-Bronchiectasis-Sinusitis Syndrome Immotile Cilia Syndrome, Kartagener Type Primary Ciliary Dyskinesia And Situs Inversus Primary Ciliary Dyskinesia, Kartagener Type Siewert Syndrome Dyskinesia, Ciliary, Primary
Congenital Nervous System Abnormality	Congenital Neurologic Anomaly Congenital Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-12124	BBS-4	Inhibitor	99.49%	Unkown
HY-RS01388	BBS4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS17738	Bbs4 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24203	Bbs4 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Mus musculus	BBS4	MGD	MGI:2143311
Rattus norvegicus	BBS4	RGD	RGD:1309134