BBIP1 - BBSome interacting protein 1 Gene

Also Known as BBS18; BBIP10; bA348N5.3; NCRNA00081

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 92482

Summary

This gene encodes one of eight proteins that form the BBSome complex and is essential for its assembly. The BBSome complex is involved in trafficking signal receptors to and from the cilia. Mutations in this gene result in Bardet-Biedl syndrome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

BBIP1 Products (1)

mRNA Protein Name
NM_001195305.3 NP_001182234.1 BBSome-interacting protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19081074 GOA
Biological Process GO Annotation Evidence References Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
19081074 GOA
Cellular Component GO Annotation Evidence References Source
part of BBSome IDA
IDA: Inferred from direct assay
19081074 GOA
part of BBSome IPI
IPI: Inferred from physical interaction
19081074 GOA
located in ciliary membrane IDA
IDA: Inferred from direct assay
19081074 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
19081074 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BBSome-interacting protein 1

  • BBSome-interacting protein of 10 kDa

  • UPF0604 protein

BBIP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
BBIP1 A8MTZ0 BBS4 Homo sapiens Q96RK4
Y2H
29039417
Intra
BBIP1 A8MTZ0 BBS4 Homo sapiens Q96RK4
Anti Tag CoIP
22500027
Intra
BBIP1 A8MTZ0 BBS4 Homo sapiens Q96RK4
Lumier
29039417
Intra
BBIP1 A8MTZ0 BBS4 Homo sapiens Q96RK4
Density Sedimentation
19081074
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01562 BNIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01623 BRIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20866 Brip1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27381 Brip1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown