HMN-1180
HMN-1180 is a selective, competitive neuronal nitric oxide synthase (nNOS) inhibitor with a Ki value of 5.4 μM against rat nNOS. HMN-1180 exerts no significant effect on endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS). HMN-1180 inhibits nitric oxide production. HMN-1180 can be used for the study of nNOS-related neuronal functional physiology.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 221134-00-5
- 分子式: C15H19N3O2S
- 分子量:305.40
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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nNOS 5.4 (rat) μM (Ki) |
HMN-1180 acts as a selective, competitive inhibitor of rat neuronal nitric oxide synthase (nNOS) with a Ki of 5.4 μM, does not inhibit eNOS or iNOS at concentrations up to 30 μM, and blocks nNOS-mediated NO production in human neuroblastoma SK-N-MC cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 221134-00-5
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分子量 305.40
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分子式 C15H19N3O2S
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SMILES
O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
HMN-1180 関連分類
HY-182519 関連分類
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