LSD1-IN-42
LSD1-IN-42 (Compound 7ae) is an orally active LSD1 inhibitor that potently inhibits LSD1 activity (IC50 = 0.08 μM). LSD1-IN-42 downregulates PD-L1 expression and enhances T cell-mediated tumor killing effects. LSD1-IN-42 demonstrates significant anti-gastric cancer activity by inhibiting tumor cell invasion and migration.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C22H20ClN3O7S
- 分子量:505.93
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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LSD1 0.08 μM (IC50) |
化学情報
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分子量 505.93
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分子式 C22H20ClN3O7S
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SMILES
O=C1OCC(C1=C)C(O)C2=CN(C3=C2C=C(C=C3)Cl)S(=O)(C4=CC=C(C([N+]([O-])=O)=C4)N(C)C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)