Mal-PEG2-bis-PEG3-BCN
Based on 1 Customer Validation
Mal-PEG2-bis-PEG3-BCN is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-bis-PEG3-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.33%
- CAS 番号: 2882973-13-7
- 分子式: C61H95N7O20
- 分子量:1246.44
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2882973-13-7
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性状 Solid-Liquid Mixture
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分子量 1246.44
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分子式 C61H95N7O20
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Color Light yellow to yellow
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SMILES
[H][C@@]12[C@@](CCC#CCC2)([H])[C@@H]1COC(NCCOCCOCCOCCNC(CCOCC(NC(CCOCCOCCNC(CCN3C(C=CC3=O)=O)=O)=O)COCCC(NCCOCCOCCOCCNC(OC[C@@H]4[C@@]5(CCC#CCC[C@@]54[H])[H])=O)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : 100 mg/mL (80.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8023 mL | 4.0114 mL | 8.0228 mL | 20.0571 mL |
| 5 mM | 0.1605 mL | 0.8023 mL | 1.6046 mL | 4.0114 mL | |
| 10 mM | 0.0802 mL | 0.4011 mL | 0.8023 mL | 2.0057 mL | |
| 15 mM | 0.0535 mL | 0.2674 mL | 0.5349 mL | 1.3371 mL | |
| 20 mM | 0.0401 mL | 0.2006 mL | 0.4011 mL | 1.0029 mL | |
| 25 mM | 0.0321 mL | 0.1605 mL | 0.3209 mL | 0.8023 mL | |
| 30 mM | 0.0267 mL | 0.1337 mL | 0.2674 mL | 0.6686 mL | |
| 40 mM | 0.0201 mL | 0.1003 mL | 0.2006 mL | 0.5014 mL | |
| 50 mM | 0.0160 mL | 0.0802 mL | 0.1605 mL | 0.4011 mL | |
| 60 mM | 0.0134 mL | 0.0669 mL | 0.1337 mL | 0.3343 mL | |
| 80 mM | 0.0100 mL | 0.0501 mL | 0.1003 mL | 0.2507 mL |
Mal-PEG2-bis-PEG3-BCN 関連分類
HY-136060 関連分類
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