MALT1-IN-8
MALT1-IN-8 is a potent MALT1 protease inhibitor with a IC50 of 2 nM. MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells with an IC50 of 1.16 μM. MALT1-IN-8 has anticancer effects (WO2018165385A1; Compound 8).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2244109-29-1
- 分子式: C20H15Cl2N7O
- 分子量:440.29
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
IC50: 2 nM (MALT1 protease)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| OCI-Ly3 | EC50 |
0.99 μM
Compound: 15
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Antiproliferative activity against human OCILY3 cells by cell proliferation assay
Antiproliferative activity against human OCILY3 cells by cell proliferation assay
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[PMID: 31129051] |
化学情報
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CAS 番号 2244109-29-1
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分子量 440.29
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分子式 C20H15Cl2N7O
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SMILES
O=C(NC1=CC(Cl)=C(N2N=CC=N2)N=C1)NC3=C(C4CC4)C5=CC(Cl)=CC=C5N=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
MALT1-IN-8 関連分類
HY-143426 関連分類
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