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製品番号: HY-109037R

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Mavacamten (Standard)

(別名: MYK461 (Standard); SAR439152 (Standard))

1 Cited Publications

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Mavacamten (Standard) is the analytical standard of Mavacamten. This product is intended for research and analytical applications. Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC₅₀s of 490, 711 nM for bovine cardiac and human cardiac, respectively.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度: 99.74%
CAS 番号: 1642288-47-8
分子式: C₁₅H₁₉N₃O₂
分子量:273.33

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Mavacamten (Standard) 構造式

CAS 番号: 1642288-47-8

容量

価格（税別）

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Amount: USD 0.00

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information

説明

アプリケーション

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

化学情報

CAS 番号 1642288-47-8
性状 Solid
分子量 273.33
分子式 C₁₅H₁₉N₃O₂
Color White to off-white
SMILES

CC(N(C1=O)C(C=C(N[C@H](C2=CC=CC=C2)C)N1)=O)C
別名

MYK461 (Standard); SAR439152 (Standard)
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Physiol Rep

Mavacamten facilitates myosin head ON-to-OFF transitions and shortens thin filament length in relaxed mouse skeletal muscle. [Abstract]

2025 Oct;13(20):e70606. PMID: 41144950

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

参考文献

[1]. Kawas RF, et al. A small-molecule modulator of cardiac myosin acts on multiple stages of the myosin chemomechanical cycle. J Biol Chem. 2017 Oct 6;292(40):16571-16577. [Content Brief]

[2]. Stern JA, et al. A Small Molecule Inhibitor of Sarcomere Contractility Acutely Relieves Left Ventricular Outflow Tract Obstruction in Feline Hypertrophic Cardiomyopathy. PLoS One. 2016 Dec 14;11(12):e0168407. [Content Brief]

[3]. Green EM, et al. A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice. Science. 2016 Feb 5;351(6273):617-21. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Mavacamten (Standard)

1 Cited Publications

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化学情報
Publications (1)
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Mavacamten (Standard)

MedChemExpress（MCE）の使用を引用している文献 Mavacamten (Standard)

Product Information

化学情報

Publications (1)

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Mavacamten (Standard) 関連分類

HY-109037R 関連分類