1642288-47-8
1642288-47-8
Chemical Structure
Mavacamten
Synonym(s): MYK461; SAR439152
- CAS No.: 1642288-47-8
- Formula:C15H19N3O2
- Molecular Weight:273.34
IUPAC Name: (S)-3-isopropyl-6-((1-phenylethyl)amino)pyrimidine-2,4(1H,3H)-dione
InChIKey: RLCLASQCAPXVLM-NSHDSACASA-N
SMILES: CC(N(C1=O)C(C=C(N[C@H](C2=CC=CC=C2)C)N1)=O)C
Biological Activity: Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mavacamten | 99.98% | Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. | ||||||||||||||||||||
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Mavacamten (Standard) | 99.74% | Mavacamten (Standard) is the analytical standard of Mavacamten. This product is intended for research and analytical applications. Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. | ||||||||||||||||||||
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Mavacamten-d6 | Mavacamten-d6 (MYK461-d6; SAR439152-d6) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. | |||||||||||||||||||||
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Mavacamten-d7 | 99.68% | Mavacamten-d7 (MYK461-d7) is deuterium labeled Mavacamten. Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. | ||||||||||||||||||||
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Mavacamten-d1 | Mavacamten-d1 (MYK461-d1; SAR439152-d1) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. | |||||||||||||||||||||
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Mavacamten-d5 | 98.01% | Mavacamten-d5 (MYK461-d5; SAR439152-d5) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. | ||||||||||||||||||||
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