Multi-kinase-IN-3
Multi-kinase-IN-3 (compound 2) is a potent angiokinase inhibitor. Multi-kinase-IN-3 shows inhibition activity against VEGFR-2 and PDGFRβ, with IC50 values of 58.3 and 55 nM, respectively.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2091950-43-3
- 分子式: C33H33N5O3
- 分子量:547.65
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
VEGFR アイソフォーム固有の製品をすべて表示
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生物活性
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PDGFRβ 55 ± 2.6 nM (IC50) |
VEGFR-2 58.3 ± 5.9 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
30.42 μM
Compound: 8h
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Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
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[PMID: 28190652] |
| HT-29 | IC50 |
3.12 μM
Compound: 8h
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Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
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[PMID: 28190652] |
| SK-OV-3 | IC50 |
25.87 μM
Compound: 8h
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Antiproliferative activity against human SKOV3 cells after 72 hrs by MTT assay
Antiproliferative activity against human SKOV3 cells after 72 hrs by MTT assay
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[PMID: 28190652] |
化学情報
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CAS 番号 2091950-43-3
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分子量 547.65
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分子式 C33H33N5O3
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SMILES
O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N4C=CC=C4CN5CCN(C)CC5)C=C3)/C6=CC=CC=C6)OC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Multi-kinase-IN-3 関連分類
HY-150027 関連分類
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