NNRT-IN-14
NNRT-IN-14 is an HIV-1 reverse transcriptase inhibitor (IC50 = 0.175 µM). NNRT-IN-14 can form hydrogen bonds with LYS101, PRO225, and PHE227, and π–π stacking with TYR181 and TRP229. NNRT-IN-14 can be used for the study of HIV.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C25H18N6O
- 分子量:418.45
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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HIV-1 0.175 μM (IC50) |
NNRT-IN-14 (Compound 19a) (1 μM, 1 h) shows an inhibition rate of 84.86% against HIV-1 RT, with an IC50 value of 0.175 μM[1].
NNRT-IN-14 (50 μg/mL, 48 h) shows no significant toxicity to either cancer cells or normal cells (IC50 > 119.5 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 418.45
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分子式 C25H18N6O
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SMILES
CC1=C(OC2=C(C=NC=C3)C3=NC(NC4=CC=C(C#N)C=N4)=C2)C(C)=CC(/C=C/C#N)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
NNRT-IN-14 関連分類
HY-178923 関連分類
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