Nrf2 activator-10
Based on 1 Customer Validation
Nrf2 activator-10 (Compound AI-1) is a PI3K-dependent inducer for antioxidant response element (ARE) (EC50 is 2.7 μM) and an activator for Nrf2. Nrf2 activator-10 modifies Keap1, blocks Cul3-Keap1 ubiquitin ligase complex, activates the transcription of Nrf2. Nrf2 activator-10 protects cells from H2O2-induced apoptosis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.65%
- CAS 番号: 75483-04-4
- 分子式: C13H12ClNO3
- 分子量:265.69
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Cell Death Library
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
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Bioactive Compound Library
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Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library
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High-Throughput Bioactive Compound Library
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Lactylation Compound Library
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Apoptosis Compound Library
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Immunology/Inflammation Compound Library
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Stem Cell Signaling Compound Library
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Anti-Cancer Compound Library
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生物活性
化学情報
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CAS 番号 75483-04-4
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性状 Solid
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分子量 265.69
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分子式 C13H12ClNO3
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Color White to off-white
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SMILES
O=C(C1=C(Cl)C2=C(C=CC=C2)N(C)C1=O)OCC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (188.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7638 mL | 18.8189 mL | 37.6378 mL | 94.0946 mL |
| 5 mM | 0.7528 mL | 3.7638 mL | 7.5276 mL | 18.8189 mL | |
| 10 mM | 0.3764 mL | 1.8819 mL | 3.7638 mL | 9.4095 mL | |
| 15 mM | 0.2509 mL | 1.2546 mL | 2.5092 mL | 6.2730 mL | |
| 20 mM | 0.1882 mL | 0.9409 mL | 1.8819 mL | 4.7047 mL | |
| 25 mM | 0.1506 mL | 0.7528 mL | 1.5055 mL | 3.7638 mL | |
| 30 mM | 0.1255 mL | 0.6273 mL | 1.2546 mL | 3.1365 mL | |
| 40 mM | 0.0941 mL | 0.4705 mL | 0.9409 mL | 2.3524 mL | |
| 50 mM | 0.0753 mL | 0.3764 mL | 0.7528 mL | 1.8819 mL | |
| 60 mM | 0.0627 mL | 0.3136 mL | 0.6273 mL | 1.5682 mL | |
| 80 mM | 0.0470 mL | 0.2352 mL | 0.4705 mL | 1.1762 mL | |
| 100 mM | 0.0376 mL | 0.1882 mL | 0.3764 mL | 0.9409 mL |
Nrf2 activator-10 関連分類
HY-124834 関連分類
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