PAANIB-1
PAANIB-1 is a parthanatos associated apoptosis-inducing factor nuclease (PAAN)/macrophage migration inhibitor factor (MIF) inhibitor. PAANIB-1 exhibits neuroprotective activity. PAANIB-1 can be used for the research of Parkinson's disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2634726-71-7
- 分子式: C62H81FN6O15
- 分子量:1169.34
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
PAANIB-1 (Compound 154) (10 μM; 1 h preincubation) inhibits 38.2% MIF activity and protects SH-SY5Y cells against MNNG (HY-128612)-induced cell death[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:SH-SY5Y human neuroblastoma cells
-
Concentration:10 μM
-
Incubation Time:1 h (pre-incubation); 15 min (MNNG)
-
Result:Reduced 46.2% MNNG-induced cell death in SH-SY5Y cells.
化学情報
-
CAS 番号 2634726-71-7
-
分子量 1169.34
-
分子式 C62H81FN6O15
-
SMILES
O=C1N2[C@@](C(N(CC/C=C/C(OCC(C)(C(C(N3[C@](CCCC3)([H])C(O[C@@H](C4=CC(F)=CC(OCC(N([C@H](C(N[C@@H](C5=CC=CC=C5)C(N([C@H]1COC(C)(C)C)C)=O)=O)C)C)=O)=C4)CCC6=CC(OC)=C(C=C6)OC)=O)=O)=O)C)=O)C)=O)([H])CCC2
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
PAANIB-1 関連分類
HY-182935 関連分類
Powered by Bioz