PIM1-IN-6
PIM1-IN-6 (compound 5h) is a potent PIM-1 inhibitor, with an IC50 of 0.60 μM. PIM1-IN-6 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 1.51 and 15.2 μM, respectively.
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- CAS 番号: 2439168-69-9
- 分子式: C21H18N6O4
- 分子量:418.41
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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PIM1 0.60 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
1.51 μM
Compound: 44
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Anticancer activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
Anticancer activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
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[PMID: 34438126] |
化学情報
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CAS 番号 2439168-69-9
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分子量 418.41
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分子式 C21H18N6O4
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SMILES
O=C(C1=C2NC(C=C(C3=CC=CC=C3)N2N=C1NCC)=O)NC4=CC=C([N+]([O-])=O)C=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
PIM1-IN-6 関連分類
HY-147920 関連分類
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