2439168-69-9
2439168-69-9
Chemical Structure
PIM1-IN-6
- CAS No.: 2439168-69-9
- Formula:C21H18N6O4
- Molecular Weight:418.41
IUPAC Name: 2-(ethylamino)-N-(4-nitrophenyl)-5-oxo-7-phenyl-4,5-dihydropyrazolo[1,5-a]pyrimidine-3-carboxamide
InChIKey: YFGXDAAWMNUGNN-UHFFFAOYSA-N
SMILES: O=C(C1=C2NC(C=C(C3=CC=CC=C3)N2N=C1NCC)=O)NC4=CC=C([N+]([O-])=O)C=C4
Biological Activity: PIM1-IN-6 (compound 5h) is a potent PIM-1 inhibitor, with an IC50 of 0.60 μM. PIM1-IN-6 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 1.51 and 15.2 μM, respectively[1].
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PIM1-IN-6 | PIM1-IN-6 (compound 5h) is a potent PIM-1 inhibitor, with an IC50 of 0.60 μM. PIM1-IN-6 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 1.51 and 15.2 μM, respectively. | |||||||||||||||||||||
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