(S)-CE-123
(S)-CE-123 is a potent, selective, and novel atypical dopamine transporter (DAT) inhibitor with an EC50 of 2.76 μM in uptake inhibition assays conducted in HEK293 cells stably expressing human isoforms of DAT. (S)-CE-123, a Modafinil analogue, is able to penetrate the blood–brain barrier. (S)-CE-123 improves cognitive and motivational processes in experimental animals.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2378384-49-5
- 分子式: C17H15NOS2
- 分子量:313.44
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Trained rats (adult male Sprague-Dawley rats)[1]
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Dosage:6.0, 12.0, 24.0 mg/kg
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Administration:IP; 30 min before testing
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Result:Attenuated the effects of TBZ (1.0 mg/kg) on lever pressing and chow intake.
化学情報
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CAS 番号 2378384-49-5
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分子量 313.44
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分子式 C17H15NOS2
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SMILES
O=[S@@](CC1=CN=CS1)C(C2=CC=CC=C2)C3=CC=CC=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
溶剤 & 溶解度
The following protocol is derived from the literature and is for reference only. It is recommended to first try a small sample.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)