country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-16477A

Copy Link Print Information

Talaporfin

(別名: ME2906 free acid; Mono-L-aspartyl chlorin e6 free acid; NPe6 free acid)

4 Cited Publications

カスタマーレビュー

Based on 4 publication(s) in Google Scholar

Talaporfin sodium, can be used in intraoperative photodynamic therapy (PDT) with a 664-nm semiconductor laser, was evaluated for efficacy and safety in treating primary malignant parenchymal brain tumors.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 110230-98-3
分子式: C₃₈H₄₁N₅O₉
分子量:711.76

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

Talaporfin 構造式

CAS 番号: 110230-98-3

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	181 μM Compound: Talaporfin	Dark toxicity in human A549 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay Dark toxicity in human A549 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay	[PMID: 33744687]
A549	IC₅₀	256 μM Compound: Talaporfin	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay	[PMID: 32846322]
A549	IC₅₀	6.21 μM Compound: Talaporfin	Phototoxicity in human A549 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay Phototoxicity in human A549 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay	[PMID: 33744687]
A549	IC₅₀	8.73 μM Compound: Talaporfin	Phototoxicity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs followed by irradiated with 10 J/cm2 660 nanometer visible light and measured after 24 hrs hrs by CCK-8 assay Phototoxicity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs followed by irradiated with 10 J/cm2 660 nanometer visible light and measured after 24 hrs hrs by CCK-8 assay	[PMID: 32846322]
B16-F10	IC₅₀	14 μM Compound: Talaporfin	Phototoxicity against mouse B16-F10 cells assessed as reduction in cell viability incubated for 24 hrs followed by irradiated with 10 J/cm2 660 nanometer visible light and measured after 24 hrs hrs by CCK-8 assay Phototoxicity against mouse B16-F10 cells assessed as reduction in cell viability incubated for 24 hrs followed by irradiated with 10 J/cm2 660 nanometer visible light and measured after 24 hrs hrs by CCK-8 assay	[PMID: 32846322]
B16-F10	IC₅₀	16.43 μM Compound: Talaporfin	Cytotoxicity against mouse B16-F10 cells incubated for 48 hrs under 10 J/cm2 light irradiation at 660 nm by CCK-8 assay Cytotoxicity against mouse B16-F10 cells incubated for 48 hrs under 10 J/cm2 light irradiation at 660 nm by CCK-8 assay	[PMID: 37690263]
B16-F10	IC₅₀	276.2 μM Compound: Talaporfin	Cytotoxicity against mouse B16-F10 cells incubated for 48 hrs under dark condition by CCK-8 assay Cytotoxicity against mouse B16-F10 cells incubated for 48 hrs under dark condition by CCK-8 assay	[PMID: 37690263]
B16-F10	IC₅₀	303 μM Compound: Talaporfin	Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay	[PMID: 32846322]
HCT-116	IC₅₀	2.95 μM Compound: Talaporfin	Phototoxicity in human HCT-116 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay Phototoxicity in human HCT-116 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay	[PMID: 33744687]
HCT-116	IC₅₀	50.72 μM Compound: Talaporfin	Dark toxicity in human HCT-116 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay Dark toxicity in human HCT-116 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay	[PMID: 33744687]
HeLa	IC₅₀	>300 μM Compound: Talaporfin	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay	[PMID: 32846322]
HeLa	IC₅₀	5.92 μM Compound: Talaporfin	Phototoxicity against human HeLa cells assessed as reduction in cell viability incubated for 24 hrs followed by irradiated with 10 J/cm2 660 nanometer visible light and measured after 24 hrs hrs by CCK-8 assay Phototoxicity against human HeLa cells assessed as reduction in cell viability incubated for 24 hrs followed by irradiated with 10 J/cm2 660 nanometer visible light and measured after 24 hrs hrs by CCK-8 assay	[PMID: 32846322]
HepG2	IC₅₀	>300 μM Compound: Talaporfin	Cytotoxicity against human HepG2 cells incubated for 48 hrs under dark condition by CCK-8 assay Cytotoxicity against human HepG2 cells incubated for 48 hrs under dark condition by CCK-8 assay	[PMID: 37690263]
HepG2	IC₅₀	8.9 μM Compound: Talaporfin	Cytotoxicity against human HepG2 cells incubated for 48 hrs under 10 J/cm2 light irradiation at 660 nm by CCK-8 assay Cytotoxicity against human HepG2 cells incubated for 48 hrs under 10 J/cm2 light irradiation at 660 nm by CCK-8 assay	[PMID: 37690263]

臨床実験

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

化学情報

CAS 番号 110230-98-3
分子量 711.76
分子式 C₃₈H₄₁N₅O₉
SMILES

O=C(O)C[C@@H](C(O)=O)NC(C/C1=C2[C@@H](CCC(O)=O)[C@H](C)C(/C=C3C(C)=C(C=C)/C(N/3)=C/C(C(C)=C/4CC)=NC4=C/C5=C(C)C(C(O)=O)=C1N5)=N\2)=O
別名

ME2906 free acid; Mono-L-aspartyl chlorin e6 free acid; NPe6 free acid
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (4)

All

Sort by:

Journal Impact Factor

Adv Funct Mater

09 September 2021.
Chemrxiv

2025 Aug 28.
Biomed Pharmacother

Repurposing anti-cancer porphyrin derivative drugs to target SARS-CoV-2 envelope. [Abstract]

2024 Jul:176:116768. PMID: 38795638
Patent

US20230365577A1.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (277 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Phase II clinical study on intraoperative photodynamic therapy with talaporfin sodium and semiconductor laser in patients with malignant brain tumors

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Talaporfin

4 Cited Publications

100 mg お問い合わせ

Subscribe to the

MedChemExpress

Newsletter

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ

Amount: USD 0.00

生物活性
- 製品説明
- 臨床実験
化学情報
Publications (4)
純度とドキュメンテーション
参考文献

製品名:
製品番号:
数量:
日本の代理先をお選びください:

製品名:
CAS 番号:
生物種:
純度:
数量:

Talaporfin

MedChemExpress（MCE）の使用を引用している文献 Talaporfin

生物活性

化学情報

Publications (4)

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Talaporfin 関連分類

HY-16477A 関連分類