Tildacerfont-d8
Based on 1 Customer Validation
Tildacerfont-d8 (SPR001-d8; LY2371712-d8) is a deuterium labeled Tildacerfont (HY-113603). Tildacerfont (SPR001; LY2371712) is an orally active, blood-brain barrier-penetrant selective corticotropin-releasing factor type 1 (CRF1) receptor antagonist. Tildacerfont selectively blocks CRF1 receptors, thereby inhibiting the release of pituitary adrenocorticotropic hormone (ACTH). Tildacerfont can be used in research related to congenital adrenal hyperplasia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.97%
- CAS 番号: 2762751-36-8
- 分子式: C20H18D8ClN5OS
- 分子量:428.02
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 2762751-36-8
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非標識Cas 1014983-00-6
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性状 Solid
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分子量 428.02
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分子式 C20H18D8ClN5OS
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Color White to off-white
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SMILES
CC1=NN(C(C(CC)CC)=CC(C)=N2)C2=C1C3=C(Cl)N=C(N4C([2H])([2H])C([2H])([2H])OC([2H])([2H])C4([2H])[2H])S3
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別名
SPR001-d8; LY2371712-d8
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 100 mg/mL (233.63 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3363 mL | 11.6817 mL | 23.3634 mL | 58.4085 mL |
| 5 mM | 0.4673 mL | 2.3363 mL | 4.6727 mL | 11.6817 mL | |
| 10 mM | 0.2336 mL | 1.1682 mL | 2.3363 mL | 5.8408 mL | |
| 15 mM | 0.1558 mL | 0.7788 mL | 1.5576 mL | 3.8939 mL | |
| 20 mM | 0.1168 mL | 0.5841 mL | 1.1682 mL | 2.9204 mL | |
| 25 mM | 0.0935 mL | 0.4673 mL | 0.9345 mL | 2.3363 mL | |
| 30 mM | 0.0779 mL | 0.3894 mL | 0.7788 mL | 1.9469 mL | |
| 40 mM | 0.0584 mL | 0.2920 mL | 0.5841 mL | 1.4602 mL | |
| 50 mM | 0.0467 mL | 0.2336 mL | 0.4673 mL | 1.1682 mL | |
| 60 mM | 0.0389 mL | 0.1947 mL | 0.3894 mL | 0.9735 mL | |
| 80 mM | 0.0292 mL | 0.1460 mL | 0.2920 mL | 0.7301 mL | |
| 100 mM | 0.0234 mL | 0.1168 mL | 0.2336 mL | 0.5841 mL |
Tildacerfont-d8 関連分類
HY-113603S 関連分類
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