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Voxalatamab

(別名: JNJ-63898081; JNJ-081)
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Based on 1 Customer Validation

Voxalatamab (JNJ-63898081) is a bispecific IgG4 antibody targeting PSMA and CD3. Voxalatamab attacks PSMA-expressing tumor cells by activating T cells. Voxalatamab has anticancer activity and is being studied for the treatment of solid tumors such as prostate cancer.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 99.90%
  • CAS 番号: 2411871-58-2
  • 分子量:144.68 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Voxalatamab
  • Experimental Validation Results for Voxalatamab
  • Experimental Validation Results for Voxalatamab
  • Experimental Validation Results for Voxalatamab
  • Voxalatamab Chemical Structure
    Voxalatamab 構造式
CAS 番号: 2411871-58-2
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Ig(G4-kappa_G4-lambda2)

  • 1/16

    Immobilized Human CD3 epsilon/CD3e Protein (ECD, His Tag) can bind Voxalatamab. The EC50 for this effect is 4.79 ng/mL.

  • 1/16

    Immobilized Human PSMA/FOLH1 Protein can bind Voxalatamab. The EC50 for this effect is 47.87 ng/mL.

  • 1/16

    Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Voxalatamab (HY-P99517). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control.

  • Voxalatamab Chemical Structure
    1/16
  • Voxalatamab
  • Immobilized Human CD3 epsilon/CD3e Protein (ECD, His Tag) can bind Voxalatamab. The EC50 for this effect is 4.79 ng/mL.
  • Immobilized Human PSMA/FOLH1 Protein can bind Voxalatamab. The EC50 for this effect is 47.87 ng/mL.
  • Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Voxalatamab (HY-P99517). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control.
  • Ig(G4-kappa_G4-lambda2)