ZM226600
Based on 1 Customer Validation
ZM226600 is an ATP-sensitive potassium channel opener (EC50: 500 nM). ZM226600 inhibits bladder spontaneous activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.95%
- CAS 番号: 147695-92-9
- 分子式: C16H14F3NO4S
- 分子量:373.35
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
Bioactive Compound Library Max
HY-L181
-
Bioactive Compound Library
HY-L001
-
Membrane Transporter/Ion Channel Compound Library
HY-L011
-
Neuroprotective Compound Library
HY-L070
-
Potassium Channel Compound Library
HY-L119
-
Membrane Protein-targeted Compound Library
HY-L149
-
Membrane Receptor-targeted Compound Library
HY-L150
-
Ion Channel Compound Library
HY-L166
-
MCE Bioactive Compound Library
HY-L001V
-
High-Throughput Bioactive Compound Library
HY-L205
生物活性
ZM226600 (1 μM, 30 min) inhibits bladder spontaneous activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 147695-92-9
-
性状 Solid
-
分子量 373.35
-
分子式 C16H14F3NO4S
-
Color White to off-white
-
SMILES
O=C(NC1=CC=C(S(=O)(C2=CC=CC=C2)=O)C=C1)C(C)(O)C(F)(F)F
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 250 mg/mL (669.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (272 KB)
-
SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Pinna C,et al. Effect of the ATP-sensitive potassium channel opener ZM226600 on cystometric parameters in rats with ligature-intact, partial urethral obstruction. Eur J Pharmacol. 2005 May 23;516(1):71-7. [Content Brief]
[2]. Grant TL, et al. Anilide tertiary carbinols: a novel series of K+ channel openers. Trends Pharmacol Sci. 1994 Nov;15(11):402-4. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6785 mL | 13.3923 mL | 26.7845 mL | 66.9613 mL |
| 5 mM | 0.5357 mL | 2.6785 mL | 5.3569 mL | 13.3923 mL | |
| 10 mM | 0.2678 mL | 1.3392 mL | 2.6785 mL | 6.6961 mL | |
| 15 mM | 0.1786 mL | 0.8928 mL | 1.7856 mL | 4.4641 mL | |
| 20 mM | 0.1339 mL | 0.6696 mL | 1.3392 mL | 3.3481 mL | |
| 25 mM | 0.1071 mL | 0.5357 mL | 1.0714 mL | 2.6785 mL | |
| 30 mM | 0.0893 mL | 0.4464 mL | 0.8928 mL | 2.2320 mL | |
| 40 mM | 0.0670 mL | 0.3348 mL | 0.6696 mL | 1.6740 mL | |
| 50 mM | 0.0536 mL | 0.2678 mL | 0.5357 mL | 1.3392 mL | |
| 60 mM | 0.0446 mL | 0.2232 mL | 0.4464 mL | 1.1160 mL | |
| 80 mM | 0.0335 mL | 0.1674 mL | 0.3348 mL | 0.8370 mL | |
| 100 mM | 0.0268 mL | 0.1339 mL | 0.2678 mL | 0.6696 mL |
ZM226600 関連分類
HY-101256 関連分類
Powered by Bioz