147695-92-9
Chemical Structure
ZM226600
- CAS No.: 147695-92-9
- Formula:C16H14F3NO4S
- Molecular Weight:373.35
IUPAC Name: 3,3,3-trifluoro-2-hydroxy-2-methyl-N-(4-(phenylsulfonyl)phenyl)propanamide
InChIKey: LJLXQHHFAKVTNP-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(S(=O)(C2=CC=CC=C2)=O)C=C1)C(C)(O)C(F)(F)F
Biological Activity: ZM226600 is an ATP-sensitive potassium channel opener (EC50: 500 nM). ZM226600 inhibits bladder spontaneous activity[1][2].
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ZM226600 | 99.95% | ZM226600 is an ATP-sensitive potassium channel opener (EC50: 500 nM). ZM226600 inhibits bladder spontaneous activity. | ||||||||||||||||||||
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- [1]. Pinna C,et al. Effect of the ATP-sensitive potassium channel opener ZM226600 on cystometric parameters in rats with ligature-intact, partial urethral obstruction. Eur J Pharmacol. 2005 May 23;516(1):71-7. [Content Brief]
- [2]. Grant TL, et al. Anilide tertiary carbinols: a novel series of K+ channel openers. Trends Pharmacol Sci. 1994 Nov;15(11):402-4. [Content Brief]
Keywords